EMS 2010 Annual Meeting

Monday, October 25, 2010
7:00 AM–5:00 PM
	Registration	Texas Ballroom Foyer
7:00 AM– 8:30 AM
	Breakfast Meetings
	Epigenetics Special Interest Group Leaders: Janet E. Baulch, University of Maryland, Baltimore and Catherine B. Klein, New York University School of Medicine	Sundance 3
	New Technologies Special Interest Group Leaders: Brinda Mahadevan, Abbott Laboratories and Patricia A. Escobar, Boehringer Ingelheim Pharmaceuticals	Sundance 2
8:30 AM–6:30 PM
	Posters and Exhibits OPEN	Texas Ballroom E
8:30 AM–9:30 AM
	Plenary Lecture 2 Chronic Cell Stress, Cancer, and The Epigenome Chairperson: Janet E. Baulch, University of Maryland, Baltimore Lecturer: Stephen B. Baylin, The Johns Hopkins University School of Medicine	Texas Ballroom F
9:45 AM–12:15 PM
	Symposium 6 RNA Silencing: Mechanism, Biology and Responses to Environmental Stress Chairpersons: Igor Pogribny, National Center for Toxicological Research, U.S. FDA and Olga Kovalchuk, University of Lethbridge Contributing Sponsor: Elsevier (Presenting author is underlined.)	Texas Ballroom G
9:45 AM–10:15 AM	MicroRNAome Changes in Radiation-Induced Genome Instability Olga Kovalchuk, University of Lethbridge
10:15 AM–10:45 AM	*Epimutation Induction by Environmental Factors, Such As H. pylori* Infection and Smoking** Toshikazu Ushijima National Cancer Centre Research Institute
10:45 AM–11:15 AM	Small Non-Coding RNAs for Medical Practice George A.Calin, University of Texas, MD Anderson Cancer Center
11:15 AM–11:45 AM	piRNAs and Transposable Elements in the Germ-Line Alex Bortvin, Carnegie Institution
11:45 AM–12:00 NOON	MicroRNA Expression during Aflatoxin B1-Induced Hepatocarcinogenesis in HCV Transgenic and C57BL/6J Mice Volodymyr Tryndyak, National Center for Toxicological Research, U.S. FDA
12:00 NOON–12:15 PM	Epigenetic Changes in C57BL/6J Mice Induced by Short-Term Exposure to 1,3-Butadiene by Inhalation Scherhag A, Sorrentino J, PogribnyI, Rusyn I, Koturbash I
9:45 AM–12:15 PM
	Symposium 7 Cognitive Consequences of Fetal and Early Postnatal Exposure to Environmental Contaminants Chairpersons: Radim Sram, Institute of Experimental Medicine and Miriam Poirier, National Cancer Institute, NIH Organized by the Molecular Epidemiology Special Interest Group Contributing Sponosr: Office of Research in Women’s Health, NIH	Texas Ballroom F
9:45 AM–10:10 AM	Neurobehavioral Consequences of Prenatal Exposure to Phthalates in a Multiethnic Cohort Stephanie M. Engel, The Mount Sinai School of Medicine
10:10 AM–10:35 AM	Impact of Air Pollutants in the Czech Republic on Children’s Health Outcomes Radim J. Sram, Institute of Experimental Medicine
10:35 AM–11:00 AM	The Effect of Maternal Smoking during Pregnancy on Intellectual Disabilities Among 8-Year Old Children Joyce S. Nicholas, Medical University of South Carolina, Charleston
11:00 AM–11:15 AM	Break
11:15 AM–11:40 AM	*Effect of In Utero* Gene-Environment Interactions on Mental Development** Frederica P. Perera, Columbia University School of Public Health
11:40 AM–12:15 PM	Trans-Placental Exposures and Children’s Mental and Physical Health Nina T. Holland, University of California, Berkeley
12:15 PM–1:00 PM
	Business Meeting	Texas Ballroom F
1:00 PM–2:00 PM
	Student and New Investigator Brunch	Stockyards 1
1:00 PM–2:15 PM
	Lunch on your own
2:15 PM–4:30 PM
	Symposium 8 Mitochondria Mutagenesis and Disease Chairpersons: Jason H. Bielas, The Fred Hutchinson Cancer Research Center and P.J. Brooks, National Institute on Alcohol Abuse and Alcoholism Primary Sponsor: The Ellison Medical Foundation #AG-CW-0317-10 (Presenting author is underlined)	Texas Ballroom F
2:15 PM–2:35 PM	Proteins of Nucleotide and Base Excision Repair Pathways Interact in Mitochondria to Protect from Loss of Subcutaneous Fat, a Hallmark of Aging Mark Berneberg, Eberhard Karls Universität
2:35 PM–2:55 PM	Mitochondrial ROS and mtDNA Mutations: A Central Role in Cardiac Health and Aging? Peter S. Rabinovitch, University of Washington
2:55 PM–3:15 PM	Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a CHK2-Associated Mechanism in Mammalian Cells Susan P. LeDoux, University of South Alabama
3:15 PM–3:30 PM	Break
3:30 PM–3:50 PM	Mitochondrial Fusion Is Required for mtDNA Stability and Tolerance of mtDNA Mutations Marc Vermulst, University of North Carolina
3:50 PM–4:10 PM	The Mechanism and Clinical Utility of Somatic Mitochondrial Mutagenesis in Cancer Jason H. Bielas, The Fred Hutchinson Cancer Research Center
4:10 PM–4:30 PM	Evidence That MtDNA Depletion but Not Point Mutations or Deletions Causes DNA Polymerase Gamma-Related Mitochondrial Diseases Stumpf JD, Bailey CM, Spell D, Stillwagon M, Anderson KS, Copeland WC
2:15 PM–4:30 PM
	Symposium 9 Advances and Use of Toxicogenomics in Risk Assessment Chairpersons: Nagu Keshava, U.S. Environmental Protection Agency and Michael D. Waters, Integrated Laboratory Systems, Inc. Organized by the Risk Assessment Special Interest Group (Presenting author is underlined)	Texas Ballroom G
2:15 PM–2:25 PM	Introduction: The State of the Science–From Genomics to Risk Assessment Nagu Keshava, U.S. Environmental Protection Agency
2:25 PM–2:50 PM	Predicting Carcinogenicity and Mode of Action Using Conventional and Toxicogenomics Approaches Michael D. Waters, Integrated Laboratory Systems, Inc.
2:50 PM–3:15 PM	Systems Biology of Human Benzene Exposure Luoping Zhang, University of California, Berkeley
3:15 PM–3:30 PM	Break
3:30 PM–3:50 PM	Genotoxicity and Gene Expression Profiles of Organic Extracts from the Air Particles Measured in Human Cell Lines Topinka J, Hanzalova K, Libalova H, Milcova A, Schmuczerova J, Sram RJ
3:50 PM–4:10 PM	Systems Biology Approach for Understanding MOA, Dose-Response and Susceptibility of Environmental Chemicals Steve Simmons, U.S. Environmental Protection Agency
4:10 PM–4:30 PM	Advancing the Next Generation of Risk Assessment Ila Cote, U.S. Environmental Protection Agency
2:15 PM–4:30 PM
	Platform Session 1 DNA Repair Chairpersons: Mats Ljungman, University of Michigan and Christine Canman, University of Michigan Organized by the DNA Repair and Mutagenic Mechanisms Special Interest Group (Presenting author is underlined)	Texas Ballroom I
2:15 PM–2:40 PM	REV1 and DNA Polymerase ζ Facilitate Homologous Recombination Repair Canman CE
2:40 PM–3:05 PM	Structural and Functional Insights into the Non-Homologous End-Joining Pathway Lees-Miller SP
3:05 PM–3:20 PM	A Member of NER Proteins XPF Is Involved in DNA DSB Repair by MMEJ in Mammalian Cells Scuric Z, Schiestl RH
3:20 PM–3:35 PM	Break
3:35 PM–4:00 PM	Epigenetic Drugs As Modifiers of NHEJ Repair Robert C, Gojo I, Rassool F
4:00 PM–4:15 PM	A Cross-Species Approach for the Discovery of Genetic Interactions in the DNA Damage Response Piening BD, Huang D, Hsu H-M, Wang S, Murakami-Sekimata A, Wang P, Paulovich AG
4:15 PM–4:30 PM	Role of Nucleotide Excision Repair (NER) in Manifestation of Zidovudine (AZT)-Induced Aneuploidy and Centrosomal Dysregulation Momot D, Nostrand TA, Ward Y, John K, Poirier MC, Olivero OA
4:30 PM–6:30 PM
	Poster Session 2 and Exhibits	Texas Ballroom E
	Even Numbered Abstracts Attended
6:30 PM–8:30 PM
	Committee Meetings
	Education, Student and New Investigator Affairs Committee	Fort Worth 1
	Public Relations and Communications Committee	Fort Worth 2
	Membership and Professional Development Committee and Special Interest Group Leaders	Sundance 2