EMS 2010 Annual Meeting

Sunday, October 24, 2010
7:00 AM–5:00 PM
	Registration	Texas Ballroom Foyer
7:00 AM–8:30 AM
	Breakfast Meetings
	Applied Genetic Toxicology Special Interest Group Leaders: Patricia A. Escobar, Boehringer Ingelheim Pharmaceuticals and Krista L. Dobo, Pfizer Global R&D Contributing Sponsor: BioReliance Corporation	Sundance 4
	DNA Repair and Mutagenic Mechanisms Special Interest Group Leaders: Mats Ljungman, The University of Michigan Medical School and Joann B. Sweasy, Yale University School of Medicine	Sundance 3
	Transgenic and In Vivo Mutagenesis Special Interest Group Leaders: Kathleen A. Hill, The University of Western Ontario and Mugimane Manjanatha, National Center for Toxicological Research, U.S. FDA	Sundance 2
8:30 AM–9:30 AM
	Plenary Lecture 1 Genomic Disorders: Mechanisms and Assays for CNV Associated with Human Disease Traits Chairperson: William Kaufmann. University of North Carolina, Chapel Hill Lecturer: James R. Lupski, Baylor College of Medicine	Texas Ballroom F
9:45 AM–12:15 PM
	Symposium 1 Replication Stress: Environmental Causes, Cellular Responses, and Mutational Consequences Chairpersons: Andrew B. Buermeyer, Oregon State University and Philip C. Hanawalt, Stanford University Organized by the DNA Repair and Mutagenic Mechanisms Special Interest Group Supported in Part by: Phillip C. Hanawalt	Texas Ballroom F
9:45 AM–9:50 AM	Introduction
9:50 AM–10:15 AM	Whole Genome Analysis of Structural Changes Induced by Environmental Replication Stress Thomas E. Wilson, University of Michigan
10:15 AM–10:40 AM	Replication Fork Protection Proteins Timeless and Timeless-Interacting Protein (Tipin) Maintain Genomic Stability Stephanie Smith-Roe, University of North Carolina, Chapel Hill
10:40 AM–10:55 AM	Break
10:55 AM–11:20 AM	Defect of the WRN Gene, Linked to Premature Aging in Humans, Protects Mice from Tumor Development Carla Grandori, University of Washington
11:20 AM–11:45 AM	Promotion of Genomic Stability by DNA Topoisomerase I by Coordination of Transcription and Replication Yves Pommier, National Institutes of Health
11:45 AM–12:10 PM	Replication Fork Indiscretions and Genome Instability Sergei Mirkin, Tufts University
12:10 PM–12:15 PM	Discussion
9:45 AM–12:30 PM
	Symposium 2 Is Tobacco Smoke a Germ-Cell Mutagen? Chairperson: Carole Yauk, Health Canada and Francesco Marchetti, Lawrence Berkeley National Laboratory Organized by the Heritable Mutation and Disease Special Interest Group Sponsored in part by: Anonymous Contributor	Texas Ballroom G
9:45 AM–10:05 AM	Mutagenic Effects of Cigarette Smoke on Sperm in Mice and Humans Carole Yauk, Health Canada
10:05 AM–10:45 AM	Epidemiological Evidence for Increased Cancer in Descendants of Fathers Who Smoke Patricia A. Buffler, University of California, Berkeley
10:45 AM–11:00 AM	Break
11:00 AM–11:45 AM	Human Primordial Germ Cell Formation Is Diminished by Exposure to Environmental Toxicants Acting Through the AHR Signaling Pathway Renee Reijo Pera, Stanford University School of Medicine
11:45 AM–12:15 PM	Is Tobacco Smoke a Germ-Cell Mutagen? David M. DeMarini, U.S. Environmental Protection Agency
12:15 PM–12:30 PM	Discussion
12:30 PM–2:00 PM
	Lunch on your own
12:45 PM–2:00 PM
	Town Hall Meeting (Box Lunches Available) EMS Connect: Welcome to the 21st Century Led by Ofelia A. Olivero, National Cancer Institute, NIH	Texas Ballroom F
2:15 PM–4:30 PM
	Symposium 3 DNA Interstrand Crosslinks: Repair, Cell Signaling, and Therapeutic Implications Chairpersons: Karen M. Vasquez, University of Texas MD Anderson and Paul Miller, Johns Hopkins University Supported in Part by: Fanconi Anemia Research Fund	Texas Ballroom G
2:15 PM–2:35 PM	The Fanconi Anemia Pathway in DNA Interstrand Crosslink Repair Alan D’Andrea, Dana-Farber Cancer Institute
2:35 PM–2:55 PM	Targeting and Processing of Site-Specific DNA Interstrand Crosslinks Karen M. Vasquez, University of Texas MD Anderson
2:55 PM–3:15 PM	Initiation of DNA Interstrand Cross-Link Repair in Mammalian Cells Paul Miller, Johns Hopkins University
3:15 PM–3:30 PM	Break
3:30 PM–3:50 PM	Mechanisms of S-Phase Repair of DNA Interstrand Crosslinks Randy Legerski, University of Texas MD Anderson Cancer Center
3:50 PM–4:10 PM	Assessing the Link between BACH1/FANCJ and MLH1 in the DNA Damage Response Sharon B. Cantor, University of Massachusetts Medical School
4:10 PM–4:30 PM	Role of Homologous Recombination in DNA Interstrand Crosslink Repair John M. Hinz, Washington State University
2:15 PM–4:30 PM
	Symposium 4 Telomeres, Aging, and Human Disease Chairpersons: Patricia L. Opresko, University of Pittsburgh, John Murnane, University of California, San Francisco, and Chin-Rang Yang, University of Texas Southwestern Dallas	Texas Ballroom F
2:15 PM–2:35 PM	Werner Syndrome Protein and Common Fragile Site Replication Kristin A. Eckert, Pennsylvania State University College of Medicine
2:35 PM–2:55 PM	Mechanisms of Telomeric DNA Replication Woody Wright, University of Texas Southwestern, Dallas
2:55 PM–3:15 PM	Telomeric Instability and Double Strand Breaks John Murnane, University of California, San Francisco
3:15 PM–3:30 PM	Break
3:30 PM–3:50 PM	Human Diseases of Telomerase Dysfunction Christine Garcia, University of Texas Southwestern, Dallas
3:50 PM–4:10 PM	Klotho and Ageing Related Signaling Pathways in Mice Makoto Kuro-O, University of Texas Southwestern, Dallas
4:10 PM–4:30 PM	Quantitative Analysis and Mathematical Modeling of Ageing Signaling Network Chin-Rang Yang, University of Texas Southwestern, Dallas
2:15 PM–4:30 PM
	Symposium 5 Next Generation Sequencing Technology and Applications Chairpersons: James C. Fuscoe, U.S. Food and Drug Administration and Brinda Mahadevan, Abbott Laboratories Organized by the New Technologies Special Interest Group	Texas Ballroom I
2:15 PM–2:45 PM	Strategies for the Identification of Disease Causing Mutations by Complete Genome Sequencing C. Thomas Caskey, The University of Texas Health Science Center at Houston
2:45 PM–3:15 PM	Next Generation Technologies: Basics and Applications Michael L. Metzker, Baylor College of Medicine Sequencing Center
3:15 PM–3:30 PM	Break
3:30 PM–4:00 PM	Mutation Profiling in Human Cancer Using Next Generation Sequencing David A. Wheeler, Baylor College of Medicine Sequencing Center
4:00 PM–4:30 PM	Large-Scale Human Genome Sequencing for Advanced Disease Studies: Dissecting the Interplay of Genetics and Environment Radoje Drmanac, Complete Genomics, Inc.
4:30 PM–6:30 PM
	Poster Session 1 and Exhibits Odd Numbered Abstracts Attended	Texas Ballroom E
6:30 PM–8:30 PM
	Committee Meetings
	2011 Program Committee Meeting (First Meeting)	Forth Worth 1
	Awards and Honors Committee	Forth Worth 2
	Web Site Committee	Forth Worth 3