EMS 2012 Annual Meeting

Tuesday, September 11
7:00 AM–5:00 PM
		Registration	Grand Ballroom Foyer
7:00 AM–5:00 PM
		Speaker Ready Room Open	Grand Ballroom E
7:00 AM–8:30 AM
		Executive Board Meeting	Larch
7:00 AM–8:30 AM
		Breakfast Meetings Breakfast Pick-Up for Meetings (Ticket Required—Breakfast Available at 6:45 AM)	Evergreen Ballroom Foyer
		Environmental Genetic Toxicology Special Interest Group Leaders: Christopher M. Somers, University of Regina and Carol D. Swartz, Integrated Laboratory Systems	Evergreen Ballroom A
		Risk Assessment Special Interest Group Leaders: David A. Eastmond, University of California, Riverside and Nagu Keshava, US Environmental Protection Agency	Evergreen Ballroom B
		*Transgenic and In Vivo* Mutagenesis Special Interest Group** Leaders: Mugimane G Manjanatha and Nan Mei, National Center for Toxicological Research, US FDA	Evergreen Ballroom C
8:30 AM–12:00 Noon
		Posters and Exhibits Open	Evergreen Ballroom E
8:30 AM–9:30 AM
		Keynote Lecture 5 The ATM-Mediated DNA Damage Response: Moving between the Forest and the Trees Chairperson: Mats Ljungman, The University of Michigan Lecturer: Yosef Shiloh, Tel Aviv University	Grand Ballroom I
9:45 AM–12:30 PM
		Symposium 5 DNA Damage-Mediated Gene Regulation Chairpersons: Mats Ljungman, The University of Michigan and Bruce C. McKay, University of Ottawa	Grand Ballroom A
9:45 AM–10:15 AM	S21	Upstream and Downstream of Wild Type and Mutant Forms of p53 Carol Prives, Columbia University
10:15 AM–10:45 AM	S22	Posttranscriptional Regulation of the p53 Response Bruce C. McKay, University of Ottawa
10:45 AM–11:00 AM		Break (Grand Ballroom Foyer)
11:00 AM–11:30 AM	S23	Regulation of HuR Function by DNA Damage Stress-Response Kinases Miriam Gorospe, National Institute on Aging, NIH
11:30 AM–12:00 Noon	S24	Stress-Induced Regulation of the Transcriptome and RNA Stabilome Jayendra Prasad, University of Michigan
12:00 Noon–12:30 PM	S25	Toxtracker Assays: Advanced Mechanism-Based GFP Reporter Systems for Toxicity Profiling of Chemicals Harry Vrieling, Leiden University Medical Center Member
9:45 AM–12:30 PM
		Symposium 6 Mechanisms of Germ Cell Aneuploidy: Do Environmental Exposures Play a Role? Chairpersons: Francesco Marchetti, Health Canada and Kristine L. Witt, National Institute of Environmental Health Sciences Primary Sponsor:March of Dimes Foundation Grant 4-FY12-536	Grand Ballroom I
9:45 AM–10:15 AM	S26	Making Cross-Overs: Meiotic Recombination in Human Males and Females Terry Hassold, Washington State University
10:15 AM–10:45 AM	S27	Endocrine Disruptors and Gametogenesis Patricia Hunt, Washington State University
10:45 AM–11:00 AM		Break (Grand Ballroom Foyer)
11:00 AM–11:30 AM	S28	Sperm Aneuploidy Associated with Lifestyle and Work Exposures Wendie A. Robbins, University of California Los Angeles
11:30 AM–12:00 Noon	S29	Xenoestrogens Cause Aneuploidy in the Sperm and Offspring of Fish Irvin R. Schultz, Battelle Pacific Northwest National Laboratory
12:00 Noon–12:30 PM	S30	Gene-Environment Interactions in Transplacental Ovarian Toxicity and Tumorigenesis Ulrike Luderer, University of California, Irvine
12:30 PM–2:00 PM
		Lunch on Your Own
12:30 PM–2:00 PM
		Women in the EMS Special Interest Group Lunch Meeting (Advance Registration Required) Leaders: Barbara L. Parsons, National Center for Toxicological Research, US FDA and Kristine L. Witt, National Institute of Environmental Health Sciences	Evergreen Ballroom A
2:00 PM–4:00 PM
		Platform Session 5 Mutagenesis, Environmental Genomics, and Cancer Chairpersons: Lawrence A. Loeb, University of Washington and Dong Wang, University California, San Diego Underlined author indicates presenter.	Grand Ballroom A
2:00 PM–2:30 PM	29	Cancer: An Evolving Challenge Lawrence A. Loeb, University of Washington
2:30 PM–2:45 PM	30	Mutation Rate As a Therapeutic Target in Cancer Fox EJ, Shen J-C, Prindle MJ, Kaur-Rayar J, Essigmann JM, Loeb LA
2:45 PM–3:00 PM	31	Mutational Consequences of Altered DNA Precursor Pools Schaaper RM, Ahluwalia D, Bienstock RJ
3:00 PM–3:15 PM	32	Dissecting Chemical Interactions and Impact of DNA Lesions on RNA Polymerase II Transcriptional Fidelity Wang D
3:15 PM–3:30 PM	33	The Role of Reactive Oxygen Species in Cisplatin Cytotoxicity Marullo R, Degtyareva NP, Werner E, Ramalingam SS, Doetsch PW
3:30 PM–3:45 PM	34	Digital Quantification of Random Mitochondrial Deletions Taylor SD, Ericson NG, Prolla TA, Bielas JH
3:45 PM–4:00 PM	35	Profiling DNA Damage Pathways Activated by Chemicals with Different Mechanisms of DNA Damage Clewell R, Sun B, Thomas A, Carmichael P, White A, Andersen M
2:00 PM–4:00 PM
		Platform Session 6 Chromosome Instability Chairpersons: Ofelia A. Olivero, National Cancer Institute, NIH and Martin Arlt, University of Michigan Underlined author indicates presenter.	Grand Ballroom I
2:00 PM–2:30 PM	36	Chromosomal Instability and Aneuploidy Induced by Nucleoside Analogs Ofelia A. Olivero, National Cancer Institute, NIH
2:30 PM–2:45 PM	37	Mre11 Interacts with Cyclin-Dependent Kinase 2 to Regulate Double-Strand Break Repair Ferguson D
2:45 PM–3:00 PM	38	Separation of Intra-S Checkpoint Protein Contributions to DNA Replication Fork Protection and Genomic Stability in Human Fibroblasts Smith-Roe S, Patel S, Zhou Y, Simpson D, Rao S, Ibrahim J, Cordeiro-Stone M, Kaufmann W
3:00 PM–3:15 PM	39	The Lowest Detectable Dose of Ionizing Radiation by the Cytokinesis-Block Micronucleus Method Tucker J, Vadapalli M, Joiner M, Fenech M, Bonassi S
3:15 PM–3:30 PM	40	Telomere Dysfunction and DNA Repair Deficiency: Markers of Sensitivity to Mutagens and Carcinogens? Lim HK, Hande MP
3:30 PM–3:45 PM	41	De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of XRCC4-Dependent Nonhomologous End Joining Arlt M, Rajendran S, Birkeland S, McSweeney K, Wilson T, Glover T
3:45 PM–4:00 PM	42	Male Germ Cells Mediate Untargeted Mutations to the Maternal Genome of Offspring: Comparison of Transgenic Rodent and Fish Models Gresham CS, Norris MB, Alworth LC, Winn RN
4:15 PM–5:15 PM
		Keynote Lecture 6 The Emergence of Proactive P4 Medicine: A Revolution in Healthcare Chairperson: Lawrence A. Loeb, University of Washington Lecturer: Leroy Hood, Institute for Systems Biology	Grand Ballroom I
5:15 PM–6:15 PM
		EMS Award Lecture Oxidative DNA Damages: Search and Destroy Chairperson: Mats Ljungman, The University of Michigan Lecturer: Susan S. Wallace, University of Vermont	Grand Ballroom I
7:00 PM–12:00 Midnight
		Banquet Awards Presentations by Catherine B. Klein: Alexander Hollaender Award EMS Award EMS Service Award EMS Emerging Scientist Travel Awards Student and New Investigator Travel Awards	Evergreen Ballroom E