In their August 2017 Editor's Choice article, "Applying the erythrocyte Pig-a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation," Zhiying Ji and Matthew LeBaron describe the potential of the sperm Pig-a assay for detecting germ cell mutagens using two case study chemicals.
We are delighted Dr. Linda Birnbaum, director, NIEHS and NTP, will be speaking at our upcoming WEMGS Luncheon, Monday, September 11, from 12:15-1:45.
Late Breaking EMGS Abstract submission deadline is August 1, 2017.
You are encouraged to participate in the meeting by presenting your research as a Poster. Submission is quick and easy. Login or create an ID and password and then follow the directions and screen prompts.
In the April 2017 issue of Environmental and Molecular Mutagenesis, Yan Sha and coworkers at the Oregon Health & Science University and Vanderbilt University examined the impact of local sequence context and anomeric conformation (α or β) on Fapy-dG adduct-induced mutagenesis.
The March 2017 Editor's Choice article, "Tumor-Associated APE1 Variant Exhibits Reduced Complementation Efficiency, But Does Not Promote Cancer Cell Phenotypes" exemplifies the importance of the base excision repair protein APE1 in the preservation of cellular homeostasis and genomic integrity.