Bret David Freudenthal, PhD
‘Genome Instability and Disease’:
An EMGS Webinar and Online Workshop
Hosted by the DNA Repair and Mutagenic Mechanisms Special Interest Group
The DNA Repair and Mutagenic Mechanisms Special Interest Group will host the next EMGS Webinar and Online Workshop (WOW), titled “Genome Instability and Disease.” The workshop is open to EMGS members and guests, specifically those with an interest in DNA repair.
When: February 16 from 11am – 6pm Eastern Standard Time (U.S.)
Where: Virtual (A link will be provided to all registered participants)
Cost: Free
Details: The meeting is open to EMGS members and guests. All participants must register prior to the meeting; a link to the meeting site will be provided via email following registration.
About the series: The EMGS WOW series is designed to bring together EMGS members and members of the DNA repair community. Especially during the COVID-19 pandemic, this series will allow for interactions outside of the EMGS annual meeting with the hopes to keep moving science forward during this challenging time. We hope this event encourages non-EMGS members of the DNA Repair community to become a member of EMGS.
About this workshop: “Genome Instability and Disease,” the first of hopefully many DNA Repair SIG WOW events, is a half-day symposium designed to bring together both experts and newcomers to the field of DNA repair. The symposium will begin with a Keynote talk by Dr. Sylvie Doublie, an expert in the field of DNA Repair. This will be followed by a workshop focused on current cell-based laser approaches. The event will end with a series of talks covering a wide range of interests related to DNA repair and genome stability presented by students, post-docs, new investigators and established scientists! There is something in it for everyone.
Organizers: Drs. Aishwarya Prakash, Bret Freudenthal, and Amy Whitaker
For questions, please contact emgshq@emgs-us.org.
Not an EMGS member? Join today as a New Regular Member and receive a 50% discount on your first year of membership.
ITINERARY
11:00 am – 11:05 am: Welcome and Introduction
11:05 am – 12:00 pm
Keynote: Functional Significance of Conformational Flexibility in DNA Repair Enzymes
Dr. Sylvie Doublié, University of Vermont
Discussion Leader: Drs. Aishwarya Prakash and Amy Whitaker
12:00 pm – 12:15 pm: Break
12:15 pm – 1:15 pm:
Workshop: Current approaches on cell-based laser and light induced DNA damage and application to the study of mechanisms of genotoxicity,
Drs. Elise Fouquerel, Thomas Jefferson University; Christopher Koczor, University of South Alabama
Discussion Leader: Dr. Robert Sobol
1:15 pm – 1:30 pm: Break
1:30 pm – 2:00 pm:
The Pros and Cons of the Alkyladenine DNA Glycosylase in response to an N-nitrosamine in vivo,
Dr. Bevin Engelward, Massachusetts Institute Technology
2:00 pm – 2:30 pm:
Regulation of budding yeast Hrq1 helicase during DNA crosslink repair,
Luong Thong, University of Pittsburgh
2:30 pm – 3:00 pm:
Telomeric 8-oxoguanine drives premature senescence independently of telomere shortening,
Dr. Ryan Barnes, University of Pittsburgh
3:00 pm – 3:30 pm:
APE1 Haploinsufficiency Leads to a Significant Reduction in Mitochondrial DNA in Liver of Mice Treated with Azoxymethane,
Carmen M. Perez, University of Puerto Rico
3:30 pm – 3:45 pm: Break
3:45 pm – 4:15 pm:
UV damage repair super-hotspots and coldspots in the human genome,
Dr. Wentao Li, University of Georgia
4:15 pm – 4:45 pm:
Repair proteins are involved in DNA structure-induced genetic instability,
Dr. Guliang Wang, University of Texas
4:45 pm – 5:00 pm:
The BRCA2-interacting protein, PDS5B, and SPIDR are novel Shu complex components,
Dr. Sarah Hengel, University of Pittsburgh
5:00 pm – 5:30 pm:
Caffeine reduces UV-induced mutations of cancer-relevant genes as revealed by Duplex Sequencing,
Dr. Masaoki Kawasumi, University of Washington
5:30 pm – 6:00 pm:
DNA Repair Landscape of the NCI60 Panel of Cancer Cell Lines,
Dr. Zac Nagel, Harvard University
Adjourn
