Environmental and Molecular Mutagenesis Editor's Choice - December 2015
Both inherited genetic and non-inherited environmental factors contribute to the lifetime risk of chronic disease. Exposomics, the comprehensive study and analysis of all environmental factors, has the potential to measure the impact of individual stressors and identify novel agents that can affect the health of individuals and populations. These stressors include chemical and biological agents that occur in natural and human-constructed environments as well as the socioeconomic, political, and psychological components of well-being. Compared to conventional studies which are often limited to analyzing a small number of factors, the analytical scope of exposomics is potentially much broader. Recently, many techniques have been designed to analyze these exposomal dimensions and quantify the combined risk of multiple factors on health. To further refine and apply exposome research methods to public health endeavors, the authors propose enrolling high risk populations, such as low socioeconomic groups, migrants, and pregnant women, in exposome studies. With exposome methods and informatics now coming of age, the comprehensive overview of the field and its potential to revolutionize how public health research is conducted in “Using exposomics to Assess Cumulative Risks and Promote Health” is why the entry has been named the Environmental and Molecular Mutagenesis December 2015 Editor’s Choice article. Environ. Mol. Mutagen. 56:715-723, 2015. © 2015 Wiley Periodicals, Inc.