In their November 2020 Editor's Choice article, “Quantification of cancer driver mutations in human breast and lung DNA using targeted, error-corrected CarcSeq,” Harris et al. demonstrate spontaneously-occurring CDMs may serve as quantitative reporters of clonal expansion and carcinogenic effect.
In their October 2020 Editor's Choice article, "CD59-deficient bone marrow erythroid cells from rats treated with procarbazine and propyl-nitrosourea have mutations in the Pig-a gene," Revollo et al. report the rat RBC Pig-a assay detects true Pig-a gene mutations.
In his July’s Editor’s Choice article "A review on the 40th anniversary of the first regulation of drinking water disinfection by-products," David DeMarini concisely reviews the research and regulatory activities surrounding disinfection by-products in water.
In their June 2020 Editor's Choice article, “Image analysis of mechanistic protein biomarkers for the characterization of genotoxicants: Aneugens, clastogens, and reactive oxygen species inducers” Wilde et al. investigate PTMs as biomarkers for distinguishing between genotoxic and nongenotoxic MOA.
In their April 2020 Editor's Choice article, “Long INterspersed Element‐1 Mobility as a Sensor of Environmental Stresses” Del Re and Giorgi comprehensively review details of LINE-1, including how they function as a sensor of environmental stress.