In their July 2021 Editor’s Choice article, “Design of a digital-PCR assay to quantify fragmented human mitochondrial DNA,” Mosquera et al. describe an assay for the quantification of mtDNA copy number and DSBs resulting from biological processes or exposure to potential mitochondrial toxicants.
In their March 2021 Editor’s Choice article, Mehta et al. demonstrate DHA exposure can occur through use of sunless tanning products and e-cigarettes, and millimolar doses of the compound are genotoxic, cytotoxic and can induce metabolic reprogramming.
In their January 2021 Editor's Choice article, "A promising Ames battery for mutagenicity characterization of new dyes,” Umbuzeiro et al. propose a tiered approach for mutagenicity testing of low-quantity dyes utilizing a miniaturized Ames battery.