In their November 2020 Editor's Choice article, “Quantification of cancer driver mutations in human breast and lung DNA using targeted, error-corrected CarcSeq,” Harris et al. demonstrate spontaneously-occurring CDMs may serve as quantitative reporters of clonal expansion and carcinogenic effect.
In their October 2020 Editor's Choice article, "CD59-deficient bone marrow erythroid cells from rats treated with procarbazine and propyl-nitrosourea have mutations in the Pig-a gene," Revollo et al. report the rat RBC Pig-a assay detects true Pig-a gene mutations.
In his July’s Editor’s Choice article "A review on the 40th anniversary of the first regulation of drinking water disinfection by-products," David DeMarini concisely reviews the research and regulatory activities surrounding disinfection by-products in water.
In their June 2020 Editor's Choice article, “Image analysis of mechanistic protein biomarkers for the characterization of genotoxicants: Aneugens, clastogens, and reactive oxygen species inducers” Wilde et al. investigate PTMs as biomarkers for distinguishing between genotoxic and nongenotoxic MOA.