In their Editor's Choice article, Arlt et al. report on ionizing radiation-induced copy number variation (CNV) and suggest that any environmental agent that impairs replication is capable of inducing new CNVs.
In their Editor's Choice article, Manjanatha et al. describe their novel and hypothesis-generating observations regarding the role of genotoxicity in the mechanism(s) of doxorubicin-induced cardiotoxicity.
In the Editor's Choice article for December 2013, Dr. Suzanne Wallace describes the relationship between structure and function of the DNA glycosylases responsible for the repair of DNA damage induced by reactive oxygen species.
In the October Editor's Choice article, the 2012 Alexander Hollaender Award Winner, Marilyn Aardema reviews current thinking and regulatory posture regarding follow-up testing to deal with Ames positive results.