In the May Editor's Choice article, Dr. Salas and collaborators examined the long-term consequences of anticancer therapy used to treat Hodgkin’s lymphoma.
In the April Editor's Choice article, Dr. David M. DeMarini explains why the field of human germ-cell mutagenesis is poised for rapid progress and discusses how to meet the regulatory challenges this will present.
In the March Editor's Choice article, Urbin and colleagues demonstrated, for the first time, that cell survival and RAD51 focus formation can be separated as distinct cellular properties impacted by the RAD51 gene family of proteins.
In the January Editor's Choice article, Eric G. Thompson and co-authors show BRCA1 protects cells from error-prone repair of double-strand breaks by suppressing microhomology-mediated end joining and inhibiting mutagenesis during non-homologous end joining.
Hanssen-Bauer and colleagues developed a model including three modes of base excision, according to which three distinct complexes form through recruitment of different base excision repair proteins onto an XRCC1 core complex.