EMGS

Environmental Mutagenesis & Genomics Society

48th Annual Meeting, Raleigh, North Carolina

September 9-13, 2017 - Raleigh Convention Center

Environmental Health Sciences Bridging the Gap between
Exposure, Mechanism and Public Health

 

Welcome

The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community.  Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments or concerns.

View our EMGS Young Scientist video presentations

Agenda Overview

Environmental Health Sciences Bridging the Gap between Exposure, Mechanism and Public Health

EMGS President: Thomas E. Wilson
Program Chair: Robert W. Sobol
New Investigator Co-Chair: Natalie Gassman

Tuesday, September 12, 2017

6:30 AM
Breakfast for SIGs
Outside SIG Rooms

7:00 AM–4:00 PM
Registration Open
(1:00 PM-1:30 PM Closed for Lunch)
Main Lobby

7:00 AM–4:00 PM
Speaker Ready Room Open
(1:00 PM-1:30 PM Closed for Lunch)
Room 307

7:00 AM-8:15 AM

Special Interest Group (SIG) Meetings:

Epigenetics SIG
Room 305AB

Leaders: Caren Weinhouse, Chair; Jackie Goodrich, Co-Chair; and Kate Mueller, Student Chair

Transgenic & In Vivo Mutagenesis SIG
Room 306A

Leaders: Robert R. Young, BioReliance Corporation, Chair; Francesco Marchetti, Health Canada, Co-Chair

8:00 AM–10:00 AM
Poster Hall Open
Room 302ABC

8:30 AM–9:30 AM
Keynote Speaker 4: Dr. Mark Zylka, University of North Carolina
Topoisomerases and Environmental Risks for Brain Disorders (Sponsored by Escher Fund for Autism)
Room Ballroom A

9:30 AM–10:00 AM
Coffee Break
Outside Poster Room

10:00 AM–12:15 PM
Symposium 10:
The Genetic and Environmental Factors Associated with Autism Spectrum Disorder (Sponsored by Escher Fund for Austism and Simons Foundation)
Room 303
Chairpersons: David M. DeMarini, US EPA; Jill Escher, Escher Fund for Autism
-10:00 AM
Autism Spectrum Disorder: What it is and What it is not
Judy Van de Water, UC Davis Center for Children's Environmental Health
-10:30 AM
Grand-maternal Smoking in Pregnancy and Grandchild’s Autistic Traits and Diagnosed Autism
Jill Escher, Escher Fund for Autism
-10:50 AM
Association of Air Pollution with Risk for Autism Spectrum Disorder
Amy Kalkbrenner, University of Wisconsin-Milwaukee
-11:20 AM
Prenatal Air Pollution and Maternal Stress Alters Early Communication, Microglia and Synapse Number in Developing Offspring.
Carina Block, Duke University
-11:40 AM
Parental Age Explains the Majority of Variation in de novo Mutation Rate Within Families
Stephan Sanders, UCSF Department of Psychiatry

10:00 AM–12:15 PM
Symposium 11:
Environmental Epidemiology: The Influence of Early Life Exposures on the Epigenome
Room 301AB
Chairpersons: Jaclyn M. Goodrich, University of Michigan and Caren Weinhouse, Duke University
-10:00 AM
Prenatal Exposures and DNA Methylation at Imprinted Genes
Catherine Hoyo, North Carolina State University
-10:30 AM
Imprinting Control Regions Are Hotspots For Perturbation Of DNA Methylation By Cadmium Exposure In Mothers And Newborn Children
Michael Cowley, North Carolina State University
-10:50 AM
Epigenetics as a Mediator of Air Pollution’s Influence on Children’s Cardiovascular and Respiratory Health
Carrie Breton, University of Southern California
-11:20 AM
Maternal phthalate levels in early pregnancy are associated with infant cord blood DNA methylation
Luke Montrose, University of Michigan
-11:40 AM
Meta-Analysis of Epigenome-Wide Data for Birth Cohort Studies
Kelly Bakulski, University of Michigan

10:00 AM–12:15 PM
Symposium 12:
Microcephaly:Genetic and Environmental Contributions to Human Developmental Neuropathy
Room 304
Chairpersons: David K. Manchester, Children's Hospital Colorado and Graciela Spivak, Stanford University
-10:00 AM
Genetics and Neurobiology of Human Microcephaly: Beyond The Zika Virus
Ghayda Mirzaa,
-10:30 AM
Werner Protein Protects Against Aging and Oxidative Stress in Drosophila
Elyse Bolterstein, Northeastern Illinois University
-10:50 AM
Infections as Causes of Human Microcephaly: Rubella to Zika
David Mirsky, University of Colorado
-11:20 AM
Effects Of Autism-Relevant Cytokines And Chemokines On Neurite Outgrowth And Toxicity In The Human LUHMES Neuronal Cell Line
Lauren Matelski, University of California, Davis
-11:40 AM
Toxicology of Microcephaly
David Manchester, Childrens Colorado

12:15 PM–1:45 PM
Sigma Xi Lunch for EMGS Students and New Investigators: Communicating Science to the Public
306B

12:15 PM–1:45 PM
Committee Meetings:
SIG Leaders Committee
Room 306A
Finance and Resource Committee
Room 306C
Awards Committee
Room 305B

1:45 PM–3:30 PM
Platform Session 4:
Genome Instability and the DNA Damage Response
Room 301AB
Chairpersons: Susan S. Wallace, University of Vermont and Aishwarya Prakash, University of South Alabama
-1:45 PM
Pol γ and FEN1 fail to complement aprataxin deficieny for removal of an adenylated DNA repair intermediate during mitochondrial base excision repair
Melike Caglayan, NIH
-2:10 PM
Interaction of NEIL1 with Proteins Involved in the Replication of Nuclear and Mitochondrial DNA
Aishwarya Prakash, University of South Alabama
-2:35 PM
Molecular mechanism of DNA damage response pathway in oxidative stress
Shan Yan, University of North Carolina
-3:00 PM
Regulation of BRCA1 by SIRT2 in DNA Double-Strand Break Repair
Elizabeth Minten, Emory University

1:45 PM–3:30 PM
Platform Session 5:
Applied Genetox and Risk Assessment
Room 303
Chairpersons: Catherine Gibbons, US EPA; and Jeffrey Bemis, Litron Labs
-1:45 PM
Evaluation of Cancer Driver Mutations in Rat Tumors as Biomarkers of Human Carcinogenesis
Page B. McKinzie, National Center for Toxicological Research
-2:10 PM
Comprehensive In vitro Genotoxic Mode of Action Determination Using a One Step Multiplexed Kit, and a Machine Learning Strategy
Steven M. Bryce, Litron Laboratories
-2:35 PM
Repair Assisted Damage Detection (RADD) Harnesses DNA Repair Machinery for in situ DNA Adduct Detection
Nate W Holton, Mitchell Cancer Institute
-3:00 PM
Novel Platform for High-Throughput Cell Viability Testing
Le Ngo, MIT

1:45 PM–3:30 PM
Platform Session 6:
Dietary Exposures and Genotoxicity
Room 304
Chairpersons: Natalie Rose Gassman, University of South Alabama Mitchell Cancer Institute and  Les Hanakahi, University of Illinois
-1:45 PM
Intestinal Microbiota Involved in Genetic Instability, Genotoxicity, Inflammation, Longevity and Lymphoma Latency in Atm deficient mice - the best probiotic
Robert H. Schiestl, UCLA School of Medicine and Public Health
-2:10 PM
A direct link between topoisomerase II inhibition and DNA damage caused by Ginkgo biloba leaf extract
Nan Mei, National Center for Toxicological Research, US FDA
-2:35 PM
Assessment of liver toxicity and epigenotoxicity of the dietary supplement OxyELITE Pro
Isabelle R. Miousse, University of Arkansas for Medical Sciences
-3:00 PM
Evaluation of Black Cohosh Extract, a Popular Botanical Product, for Induction of DNA Damage and Epigenetic Changes In Vitro
Mugimane G. Manjanatha, FDA / NCTR

3:30 PM–4:30 PM
Plenary Lecture-Hollaender Award Winner: Radim J. Sram, Institute of Experimental Medicine AS CR
Air Pollution and Molecular Biomarkers Associated with Children’s Health
Room 301AB

4:30 PM–5:45 PM
EMGS Business Meeting
Room 301AB

5:45 PM–6:45 PM
Committee Meetings:
Education, Student & NI Affairs Committee
Room 306A
Public Relations and Communications Committee
Room 306B
Publication Policy Committee
Room 306C
EMGS Endowment Fund Board
Room 305B

7:00 PM–11:00 PM
EMGS Banquet
Sponsored by MilliporeSigma BioReliance(R) Services
Room Ballroom A

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