Environmental Mutagenesis & Genomics Society
49th Annual Meeting, San Antonio, Texas
September 22-26, 2018 - Hyatt Regency San Antonio
Maintaining Genomic Integrity in the Face of Environmental Insult
EMGS 2018
Meeting Microsite
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Welcome
The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community. Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments or concerns.
View Past Annual Meeting abstracts.
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Announced in: San Antonio, TX
2018 EMGS Annual Meeting
Maintaining Genomic Integrity in the Face of Environmental Insult
Sunday, September 23, 2018
6:30- 7:00 AM
Breakfast for SIG/Committee meeting attendees
7:00- 8:15 AM
SIG Meeting
New Technologies
Regency East 2
SIG Meeting
Heritable Mutation & Disease
Regency East 1
Committee Meeting
Awards/Young Scientist Award
Regency East 3
8:30- 9:30 AM
Keynote 2
Signatures of Mutational Processes in Human Cancers
Ludmil Alexandrov, University of California San Diego
Regency West
10:00- 12:00 PM
Symposium 1: Early Life Exposure to Lead and Adverse Health Effects in Children
Chairpersons: Catherine Klein and Ruth Etzel
10:00 - 10:30
Why Children are not Little Adults
Ruth Etzel, Office of Children's Health Protection, US EPA
10:30 - 11:00
A Century of Understanding and Preventing Childhood Lead Exposure
Michael Weitzman, NYU School of Medicine
11:00 - 11:30
Early Life Exposures to Lead: Effects on Fetal Growth, Neurodevelopment and the Epigenome
Robert Wright, Ichan School of Medicine at Mount Sinai, NY
11:30 - 12:00
Discussion Panel
Marc Edwards, Michael Weitzman, Robert Wright and Ruth Etzel
Regency West 6
Symposium 2: Chromosome Positioning: How the Nuclear Neighborhood Impacts DNA Repair and Gene Expression
Chairpersons: Mats Ljungman and Stephanie L. Smith-Roe
10:00 - 10:30
A 3D Code in the Human Genome
Erez Liberman Aiden, Baylor College of Medicine
10:30 - 10:45
EZH2 Mediates Cisplatin Resistance in Small Cell Lung Cancer Through Nucleotide Excision Repair
Allyson E. Koyen, Emory University
10:45 - 11:15
Chromatin and Chromosome Dynamics during DNA Double Strand Break Repair
Gaelle Legube, Centre de Biologie Integrative
11:15 - 11:30
Genome-Wide Repair Map of DNA Damage Caused by Aflatoxin in Human
Wentao Li, University of North Carolina at Chapel Hill
11:30 - 12:00
Histone Methylation and the DNA Damage Response
Kyle M. Miller, University of Texas at Austin
Regency West 4/5
Platform 1: Epigenomics and the Environment
Chairpersons: Nina Holland and Jaclyn Goodrich
10:00-10:05
Introduction
10:05-10:20
Epigenetic control of candidate susceptibility genes: Expanding the PON1 model to miRNA expression in children
Karen Huen, University of California Berkeley
10:20-10:35
Persistent DNA Methylation after Short-Term Exposure to Dichloroacetic Acid in Mice
Brian N. Chorley, US Environmental Protection Agency
10:35-10:50
Toxicogenomics-Based Derivation of a Gene Expression Signature for Histone Deacetylase Inhibitors Associated with Developmental Toxicity
Cheryl Anne Hobbs, Integrated Laboratory Systems, Inc.
10:50-11:05
Musashi-1 RNA binding protein a new biomarker candidate and therapeutic target in urothelial carcinoma
André Luiz Ventura Sávio, São Paulo State University
11:05-11:20
Modification of Comet Assay for the Assessment of global DNA Methylation Status in vitro using an endonuclease, McrBC
Mugimane Manjanatha, National Center for Toxicological Research
11:20-12:00
Questions and Discussion
Regency East 3
12:00- 1:30 PM
Lunch
Student and New Investigator Luncheon
Regency East 1
12:00- 1:30 PM
Lunch
EMM Board Meeting and Lunch
Live Oak
1:30- 3:30 PM
Symposium 3: Cancer: Bad Luck? Bad Environment? Bad Mutations? Or Something Else?
Chairpersons: Rosalie K. Elespuru and David M. DeMarini
1:30 - 2:00
The Tissue Organization Field Theory of Carcinogenesis: A Testable Replacement for the Somatic Mutation Theory
Ana Soto, Tufts University
2:00 - 2:25
Cancer: Bad Luck or Bad Environment?
Wei Zhu, Stony Brook University
2:25 - 2:45
Why the Clonal Theory of Tumor Development is Wrong
Barbara Parsons, National Center for Toxicological Research
2:45 - 3:10
Reprograming of the Epigenome by Early Life Environmental Exposures and Cancer Risk in Adulthood
Cheryl Walker, Baylor College of Medicine
3:10 - 3:30
The Halifax Project: The Role of Low Concentrations of Commonly Encountered Environmental Chemicals on Carcinogenic Risk
LeRoy Lowe, Getting to Know Cancer
Regency West 4/5
3:45- 4:45 PM
Flash Talks
3:45-3:48
Evaluation of estrogen adducts induced DNA damage and repair
Chinnadurai Mani, Mitchell Cancer Institute
3:48-3:51
Newly synthesized stilbene derivatives as a potent anti-cancer compounds
Damian Garbicz, Polish Academy of Sciences
3:51-3:54
Characterizing the Role of Glaikit in Oxidative Stress in Drosophila melanogaster
Deborah Onofrei, Northeastern Illinois University
3:54-3:57
Bioflavonoids Cause Sustained DNA damage in a Drug- and Dose-Dependent Manner that Correlate with the Promotion of Chromosomal Translocations
Donna Alice Goodenow, University of North Carolina at Charlotte
3:57-4:00
R-loops modulate trinucleotide repeat instability through DNA base excision repair
Eduardo E Laverde, Florida International University
4:00-4:03
Relationship between Modulation of Genotoxic Damage and the Endogenous Antioxidant System of Mice Treated with (-)-epigallocatechin-3-gallate and Hexavalent Chromium
Estefani Yaquelin Hernández-Cruz, UNAM
4:03-4:06
Genomic Signatures: Machine Learning and Digital Signal Processing of Genomic Sequences Provides Ultrafast and Accurate Taxonomic Classification
Gurjit Singh Randhawa, Western University
4:06-4:09
Comparison of DNA Methylation Measured by Illumina 450K and EPIC BeadChips in Blood of Newborns and 14-year-old Children
Gwen Tindula, University of California, Berkeley
4:09-4:12
Is current risk assessment of non-genotoxic carcinogens protective?
Hedwig Braakhuis, National Institute for Public Health and the Environment, Bilthoven, the Netherlands
4:12-4:15
Quantitative assessment of in vitro genotoxicity using high-throughput and high-content CometChip assay in HepaRG and HepG2 cells
Ji-Eun Seo, National Center for Toxicological Research
4:15-4:18
Optimization of 5-aza-2’deoxycytidine for Epigenetic Modification using an in vivo Mouse Model
Mathia L Colwell, University of Minnesota
4:18-4:21
Tracking down contributors to genomic signatures: Cross-species comparisons of subsequence avoidance
Maximillian Soltysiak, University of Western Ontario
4:21-4:24
Dosing Schedule of 5-aza-2’deoxycytidine as a Hypomethylating Agent in Avy Mice
Melissa Drown, University of Minnesota
4:24-4:27
FTO DIOXYGENASE STRUCTURE AND ITS INTERACTORS - BIOPHYSICAL STUDIES
Michal Marcinkowski, Institute of Biochemistry and Biophysics, PAS, Pawińskiego, Warsaw, Poland
4:27-4:30
Heterozygosity: An underappreciated meiosis-linked intrinsic mutagen in mice
Nicholas Alexander Boehler, University of Western Ontario
4:30-4:33
DNA Methylation of Ultraconserved Noncoding Elements in Atlantic Killifish (Fundulus heteroclitus) Exposed to Environmental Polycyclic Aromatic Hydrocarbons (PAHs)
Nicole Wanner, University of Minnesota
4:33-4:36
Associations between Arsenic (13 Oxidation State) Methyltransferase (AS3MT) and N-6 Adenine-specific DNA Methyltransferase1 (N6AMT1) Polymorphisms, Arsenic Metabolism, and Cancer Risk in a Chilean Population
Rosemarie de la Rosa, University of California, Berkeley
4:36-4:39
Black Raspberry Dietary Supplementation Prevents Colitis Symptoms and Colon Tumorigenesis in Mice Fed the Total Western Diet.
Sumira Phatak, Utah State University
4:39-4:42
Chromatin-bound oxidized α-Synuclein causes strand breaks in neuronal genomes in in vitro models of Parkinson’s disease
Velmarini Vasquez, Houston Methodist Research Institute
4:42-4:45
Utilization of 3D Skin Micronucleus and Comet Assay as an animal alternative model for genotoxicity positive materials in traditional in vitro studies: A Case Study
Yax Thakkar, Research Institute for Frangrance Materials