Environmental Mutagenesis & Genomics Society

49th Annual Meeting, San Antonio, Texas

September 22-26, 2018 - Hyatt Regency San Antonio

Maintaining Genomic Integrity in the Face of Environmental Insult


EMGS 2018
Meeting Microsite

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The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community.  Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments or concerns.

View Past Annual Meeting abstracts.

EMGS Local News Publicity:

Flint Water Whistleblower to S.A. Audience "Thousands of Flints Out There"

2018 EMGS Annual Meeting

Maintaining Genomic Integrity in the Face of Environmental Insult

Monday, September 24, 2018

6:30- 7:00 AM

Breakfast for SIG/Committee meeting attendees

7:00- 8:15 AM

SIG Meeting

Genetic Integrity is a Function of Epigenetic Programming in Germ Cells and Pluripotent Cells
John McCarrey, University of Texas at San Antonio

Regency East 2
SIG Meeting

Applied Genetic Toxicology
Regency East 1
Committee Meeting

Membership & Professional Development/Education, Student and New Investigator Affairs
Regency East 3
8:30- 9:30 AM
Keynote 3

Why and How Systems Biology is Revolutionizing our Science
Elaine Faustman University of Washington
Regency West

10:00- 12:00 PM

Symposium 4: Adverse Human Health Effects of Diesel Engine Exhaust
Chairpersons: David M. DeMarini and Daniel K. Carder

Diesel Engine Exhaust and Lung Cancer Risk

Michael D. Attfield, National Institute for Occupational Safety and Health

Ischemic Heart Disease and Diesel Engine Exhaust
Sadie Costello, Environmental Health Sciences, University of California Berkeley

Mutagenicity Of Emissions From Petroleum Diesel And Biodiesel: Mechanistic Insights From Bioassay-Directed Chemical Fractionation
David M. DeMarini, U.S. Environmental Protection Agency, RTP, NC

Nitrous Oxides and Particulate Matter from Diesel Exhaust: Regulatory Challenges in the Aftermath of the Volkswagen Scandal
Daniel K. Carder, Center for Alternative Fuels, Engines, and Emissions

Regency West 6
Symposium 5: Interactions among diet, metabolic status, and DNA repair: impacts on the genome and epigenome
Chairpersons: Jeffrey K. Wickliffe and Mark J. Wilson

Micronutrient Imbalance and Impacts on the Epigenome

Jaclyn Goodrich, University of Michigan School of Public Health

Enhanced Expression of Mitochondrial OGG1 Protects Against High Fat Diet-induced Obesity and Metabolic Syndrome
R. Stephen Lloyd, Oregon Health & Science University

Obesity Increases the Risk of Both Endogenous and Xenobiotic-Induced Mutagenesis
Rebecca C. Lichtler, Tulane University School of Public Health & Tropical Medicine

Regency West 4/5
Platform 2: Technologies, New Assays, and Computational Toxicology
Chairpersons: Jan van Benthem and Mark Wilson

10:00 - 10:05

10:05 - 10:20
Applying Cell Tracking Dyes and Multiplex Flow Cytometry to Increase the Throughput of the In Vitro Pig-a Gene Mutation Assay
Mark Wilson, Tulane University

10:20 - 10:35
Integration of CometChip® and TempO-Seq™: A High-Throughput 96-Well Platform to Measure and Classify DNA Damaging Agents in Human HepaRG™ Cells
Carole L. Yauk, Health Canada

10:35 - 10:50
Measurement Interference of Barcoded DNA to Determine CYP-Mediated Toxicity When Using a Direct Lysis Method
Emily A. Woolard, Oak Ridge Institute for Science and Education

10:50 - 11:05
The HET-MN (Hen´s Egg Test for Micronucleus-Induction): Pre-validation Results
Stefan Pfuhler, Procter & Gamble

11:05 - 11:20
Development Of An Adverse Outcome Pathway (AOP) Network For Carcinogenicity

Alex Nigel Cayley, Lhasa Limited

A new tool to study the formation of oxidative base damage at telomeres

Ryan Barnes, University of Pittsburgh

Untangling Adverse Outcome Pathway Networks: Extracting, Benchmarking, and Applying Emerging AOP Knowledge
Jason O'Brien, Environment and Climate Change Canada


Regency East 3
12:00- 1:30 PM
Women in the EMGS Luncheon

Maintaining work-life balance in a scientific career
Susan Mooberry, UT Health San Antonio
Regency East 1

1:30- 3:30 PM

Symposium 6: Xenobiotic exposures and fetal health
Chairpersons: Patricia Ostrosky and Maria Eugenia Gonsebatt

Transplacental Exposure to Air Pollution

Maria Eugenia Gonsebatt, Instituto de Investigaciones Biomedicas, UNAM


Elucidating the Role of Epigenetics in Fetal Epigenetic Reprogramming: Maternal Exposure to Bisphenol-A
Carolyn McCabe, University of Michigan

Transplacental Effects of Hypercaloric High-Fat Diets
Patricia Ostrosky, Director of the Instituto de Investigaciones Biomedicas, UNAM

Xenobiotic exposure and fetal health
Radim J. Sram, Institute of Experimental Medicine

Genotoxic and epigenetic effect of organophosphorus pesticides: a possible link between pesticides and their transgenerational effects
Elizabeth Rojas-García, Universidad Autónoma de Nayarit

Regency West 4/5
Symposium 7: Decline in Sperm Count and Quality: The Role of Genotoxicity and Epigenotoxicity
Chairpersons: Jackie Goodrich and Carole Yauk

Associations between Environmental Chemicals, Spermatogenesis and Non Disjunction

Melissa Perry, George Washington University


Flow cytometric measurements of acridine orange stained male germ cells is a powerful tool for determining toxicant induced cell DNA damage
Don Evenson, SCSA Diagnostic

The Male Epigenome: Chromatin Modifications and the Impact on Male Fertility and the Next Generation
Sarah Kimmins, McGill University

Do Genotoxicity Measures in Sperm Predict Genetic Effects in Offspring?

Carole Yauk, Health Canada

Regency West 6
Platform 3: Genomics and Sequencing: Technologies and Applications in Mutagenesis and Toxicology
Chairpersons: Thomas E. Wilson and Christopher Faulk

Mutation at CpG sites: The Evolution of the Epigenome and Lifespan Assessed by CpG Frequency in Conserved Promoters
Christopher Faulk, University of Minnesota

Quantification of cancer driver mutations in human lung tissues using error-corrected next-generation sequencing
Kelly Harris, US Food and Drug Administration

Gene expression profiling and epigenetic changes in healthy newborns from diverse localities in the Czech Republic
Katerina Honkova, Institution of Experimental Medicine CAS

Comparison of transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet reveal similarities that inform a non-genotoxic adverse outcome pathway for small intestine cancer
Julia E. Rager, ToxStrategies, Inc.

Adapting A Mouse Genotyping Technology To Survey Dynamics of Rodent Genomic Diversity
Rachel Kelly, University of Western Ontario

High-throughput Screening for Food Carcinogen Resistance Genes in Budding Yeast Identifies Mechanisms in DNA damage Tolerance of Carcinogen-associated DNA adducts
Michael T. Fasullo, State University of New York Polytechnic Institute
Regency East 3
3:45- 4:45 PM
Plenary Lecture: Hollaender Award Lecture

My Forty Years at the U.S. Food and Drug Administration
Robert H. Heflich, U.S. Food and Drug Administration
Regency West 4/5

4:45- 6:00 PM
Poster Session 2

Regency Center 1/3 and Foyer