Environmental Mutagenesis & Genomics Society

49th Annual Meeting, San Antonio, Texas

September 22-26, 2018 - Hyatt Regency San Antonio

Maintaining Genomic Integrity in the Face of Environmental Insult


EMGS 2018
Meeting Microsite

Access your registration information, the abstracts, view meeting attendees and more on the event microsite! Go to https://www.emgs-us.org/event/3/ and login using your email and registration code. You can find your registration code on your confirmation email and also on the back of your badge. 


The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community.  Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments or concerns.

View Past Annual Meeting abstracts.

EMGS Local News Publicity:

Flint Water Whistleblower to S.A. Audience "Thousands of Flints Out There"

2018 EMGS Annual Meeting

Maintaining Genomic Integrity in the Face of Environmental Insult

Tuesday, September 25, 2018

6:30- 7:00 AM

Breakfast for SIG/Committee meeting attendees

7:00- 8:15 AM

SIG Meeting

Risk Assessment
Regency East 2
SIG Meeting

Transgenics & In Vivo Mutagenesis
Regency East 1
Committee Meeting

Annual Meeting Publicity
Regency East 3
8:30- 9:30 AM
Plenary Lecture

EMGS Award Winner
Xeroderma pigmentosum – When the lifeguard for the gene pool goes on strike
Kenneth Kraemer, National Cancer Institute
Regency West

10:00- 12:00 PM

Symposium 8: Environmental Exposure, Genotoxicity and Cancer Risk in Whales
Chairpersons: John Pierce Wise Sr. and Daniel Martineau

A Whale of Tale: Metals and Genotoxicity in Great Whales from a One Health Approach
John Pierce Wise, University of Louisville

High Rates of Cancers in the Human and the Beluga Whale Populations of Saguenay Lac Saint-Jean, Quebec, both Extensively Exposed to PAHs, Exemplify the One Health Concept
Daniel Martineau, University of Montreal

UV-induced Damage and Photoprotection in Whales
Blanca Morales-Guerrero

Regency West 4/5
Symposium 9: Defining the spectrum of human germline variability, and exploring its environmental stimulation
Chairpersons: J. Lucas Argueso and Lizzie Ngo


Clinical incidence of germline mutations in humans
James Lupski, Baylor College of Medicine

Global patterns of germline mutagenesis in eukaryotes
Michael Lynch, Arizona State University

Absence of selection against ENU-induced point mutations in male germ cells during transmission to the next generation
Kenichi Masumura, National Institute of Health Sciences

Panel Discussion

Regency West 6
Platform 4: Mutagenesis
Chairpersons: Daniel Roberts and Page McKinzie

Missense mutations in TDP-43 and its adverse effects on genome damage repair: Implications in neurodegenerative disorders
Joy Mitra, Houston Methodist Research Institute

A systematic evaluation of the mutagenic properties of 8-oxoguanine as a function of trinucleotide sequence context
Bogdan I Fedeles, Massachusetts Institute of Technology

Genomic profiling of high-grade serous ovarian cancer cases reveals potential drivers of chromosomal instability
Irina Kovtun, Mayo Clinic

Genome-wide mutational signature of glycidamide observed in human cancers using PCAWG data
Maria M. Zhivagui, International Agency for Research on Cancer

Quantification of Actionable Cancer-Driver Mutations in African American Normal Breast and Breast Cancers, Including Triple Negative Breast Cancer
Meagan Myers, US FDA/NCTR

Methodological and Computational Approaches to using NGS for Mutation Quantitation
Page B. McKinzie, National Center for Toxicological Research
Regency East 3
12:00- 1:30 PM
SIG Meeting

Environmental Genetic Toxicology
Regency East 1
SIG Meeting

Molecular Epidemiology
Regency East 2
SIG Meeting

DNA Repair
Regency East 3

1:30- 3:30 PM

Symposium 10: Assessing, Understanding and Managing the Risks Posed by Carcinogenic PAH Mixtures
Chairpersons: Margaret Pratt and Paul White


PAH Mixtures Cancer Risk Estimation: Implementing Peer Review Recommendations and Looking Ahead

Margaret Pratt, US EPA

The Good, the Bad, and the Ugly: Polycyclic Aromatic Hydrocarbon Screening and Testing
Cynthia Rider, NTP/NIEHS

Genetic Toxicity of Complex Mixtures of Polycyclic Aromatic Hydrocarbons: Evaluating Dose-Additivity in a Transgenic Mouse Model
Alexandra Long, Health Canada

Improving Evaluation of Carcinogenic Risk for Mixtures with Systems Biology Data
Susan Tilton, Oregon State University

Remediation of a PAH-contaminated Former MGP (Manufactured Gas Plant) Site
Stephen Pinto, QM Environmental

Questions and Discussion

Regency West 4/5
Symposium 11: The Power and Promise of in vitro 3D Models for Toxicological Testing
Chairpersons: Malathi Banda and Marilyn Aardema


Review of the Use of 3D Skin Tissue models for Genotoxicity Testing
Stefan Pfuhler, Proctor and Gamble

3D Skin Micronucleus and Comet Assay for genetox positive compound: A Case Study
Shambhu Roy, MilliporeSigma

Latest Developments in Genotoxicity Testing in Non-Skin 3D Tissue Models

Jan van Benthem, National Institute for Public Health and the Environment, The Netherlands

Airway Model for Testing Inhaled Chemicals
Xuefei Cao, National Center for Toxicological Testing, US FDA

Establishing a Primary Lung Cancer Model to Identify Mutant Subpopulations That Cause Resistance to Molecularly- Targeted Cancer Therapies
Malathi Banda, Covance Laboratories Inc.


Regency West 6
Platform 5: DNA Repair 1
Chairpersons: Leslyn Hanakahi and Shobhan Gaddameedhi

Promotion of error-free transcriptional bypass of DNA lesions is essential for Rad26 to facilitate transcription coupled DNA repair
Kathiresan Selvam, Louisiana State University

Role of DNA Repair Proteins in Promoting Formation of Chromosomal Translocation
Anindita Ghosh, University of North Carolina at Charlotte

TDP-43 as a novel adjuvant target for radioimmunotherapeutic treatment of B16 melanoma
Juan Rodrigo Trujillo, Rice University

A guardian residue hinders insertion of a Fapy•dGTP analogue by modulating the open-closed DNA polymerase transition
Bret David Freudenthal, University of Kansas Medical Center

Regulation of BRCA1 by SIRT2
Elizabeth Minten, Emory University

Single-strand break end resection in genome integrity: from concept to mechanism
Shan Yan, University of North Carolina at Charlotte
Regency East 3
3:45- 4:45 PM
Plenary Lecture

Young Scientist Award Winner
Structural and biochemical studies to assess protein interactions and classify VUSs
Aishwarya Prakash, Mitchell Cancer Institute
Regency West 4/5

4:45- 5:45 PM
Business Meeting

Regency West 4/5
6:00- 7:00 PM
Emeritus/Retiree Members Group

Q Bar, Hyatt Regency Hotel
7:00- 11:00 PM
EMGS Banquet

Regency East 1/3