Environmental Mutagenesis & Genomics Society

50th Annual Meeting, Washington DC

September 19-23, 2019 - Capital Hilton Washington DC

Environmental Mutagenesis and Genomics: The Next Fifty Years

Special Symposium
Registration

 Important Dates

Registration

3/4/19-Registration is now Open
7/27/19-Early Bird Registration Ends
8/19/19-Advanced Registration Ends

Abstracts

2/22/19-Abstract Submission is now Open
5/15/19-Abstract Submission Deadline
8/29/19-Late Abstracts Deadline

Travel Awards

Travel Award Form Available
5/15/19-Travel Award Deadline

Hotel Information

2/27/19-Reservations Open
8/21/19-Reservation Deadline

Young Scientist Award


EMGS Welcomes You

The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community.  Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments.

Monday, September 23, 2019

7:00 AM - 8:00 AM

Committee Meeting

Hollaender Outreach
Committee Meeting

Diversity and Inclusion
Committee Meeting

Publication Policy

8:30 - 9:30 AM

Keynote:

Clinical Computational Oncology for Precision Cancer Medicine

Eliezer Van Allen, Broad Institute of MIT and Harvard, Cambridge, MA, USA

10:00 AM - 12:00 PM

Carcinogenic Potential of Glyphosate-Based Herbicides: Human, Animal and Mechanistic Evidence

Co-Chairs: Luoping Zhang, University of California, Berkeley, CA, USA, Maria Zhivagui, University of California, San Diego, CA, USA


10:00 - 10:30 AM
Evaluation of the Carcinogenicity of Glyphosate by the IARC Monographs Program and New Developments
Kurt Straif, Section Head, International Agency for Research on cancer (IARC), Lyon, France

10:30 - 11:00 AM

Exposure to Glyphosate-Based Herbicides and Risk for Non-Hodgkin Lymphoma: A Meta-analysis and Supporting Evidence
Luoping Zhang, Adjunct Professor, School of Public Health, University of California, Berkeley

11:00 - 11:30 AM
Effects of Glyphosate-Based Herbicides at Doses Considered Safe (US ADI): Animal Evidence
Fiorella Belpoggi, Director, Cesare Maltoni Cancer Research Center, Ramazzini Institute, Bologna, Italy

11:30 - 12:00 PM
Evaluation of Glyphosate, (Aminomethyl)phosphonic Acid, and Glyphosate-Based Formulations for Genotoxicity and Oxidative Stress Using In Vitro Approaches
Stephanie Smith-Roe, National Toxicology Program/NIEHS

 

Mutation Rates and Evolution

Co-Chairs: Joann Sweasy, Yale University, New Haven, CT, USA, Natalie Saini, NIEH


10:00 - 10:30 AM
Evolution of replication and transcription error rates across the tree of life
Michael Lynch, Center for Mechanisms of Evolution, Arizona State University

10:30 - 11:00 AM

From statistical models to biological mechanisms of human mutation
Shamil Sunyaev, Harvard University

11:00 - 11:30 AM
Somatic Mosaicism in Human Brain Development
Flora Vaccarino, Yale University Child Study Center, New Haven, CT

11:30 - 11:45 PM
TBA

 
11:45 - 12:00 PM
TBA

Platform: DNA Damage Response I


10:00-10:15 AM
Carbonyl Electrophiles Induce Topoisomerase-DNA Covalent Complexes
Les Hanakahi, University of Illinois at Chicago

10:15-10:30 AM
Repetitive DNA and Genetic Instability of the PKD1 Gene
Erik Larson, Western Michigan University

10:30-10:45 AM
High-Resolution Genome-Wide Maps of Benzo[a]pyrene-Induced DNA Damage Formation and Repair in Humans
Wentao Li, University of North Carolina School of Medicine, Chapel Hill

10:45-11:00 AM
APE2 Couples ATR-Chk1 DNA Damage Response with DNA single-strand Break Repair
Shan Yan, University of North Carolinat at Charlotte

11:00-11:15 AM
Molecular Characterization of the Telomerase Active Site
Matt Schaich, University of Kansas Medical Center

11:15-11:30 AM
Molecular Insight into APE1 Recession of 8-oxoGuanine
Amy Whitaker, University of Kansas Medical Center

11:30-11:45 AM
Cyanonitroanilines (Aminonitrobenzonitriles): Mutagenicity Studies and Characterization of a Novel Cyclic dG Adduct
David Josephy, University of Guelph

11:45-12:00 AM
Night Shift Disrupts DNA Repair and Increases DNA Damage in Humans
Bala Koritala, Washington State University

12:00 - 1:15 PM

Special Interest Group Meeting

DNA Repair

Committee Meeting

Education, Student and New Investigator Affairs

1:30 - 3:30 PM

DNA repair: The Next 50 years

Co-Chairs: Patricia Opresko, University of Pittsburgh, PA, USA, Ashwaya Prakash, University of South Alabama Mitchell Cancer Institute, USA


1:30 - 1:55 PM
Novel Precision Tools for Studying DNA Damage and Repair
Patricia Opresko, University of Pittsburgh, PA, USA

1:55 - 2:20 PM
MutSβ Stimulates Holliday Junction Resolution by the SMX Tri-Nuclease
Steve West, The Francis Crick Institute, United Kingdom

2:20 - 2:45 PM
Targeting DNA Repair: Beyond Cancer
Thomas Helleday, Karolinska Institutet, Sweden

2:45 - 3:10 PM
DNA 3R and Genome Stability
Wei Yang, NIH/DI

3:10 - 3:30 PM
Visualizing REV1 Insertion at the Molecular Level
Bret David Freudenthal, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS

DNA as a Biomarker of Human Health: Associations Between Human Mutagenesis and Genomic Instability with Disease and Implications for Regulatory Testing

Co-Chairs: Kristine Witt, DNTP/NIEHS, Clint Valentine, TwinStrand Biosciences


1:30 - 1:55 PM
Towards an Intergrated, Single-Cell Assay for the Quantitative Analysis of Genome Sequence Integrity
Jan Vijg, Albert Einstein College of Medicine

1:55 - 2:20 PM
Somatic Mutations and Brain Aging
Mike McConnell, UVA School of Medicine

2:20 - 2:45 PM
Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation
Aaron R. Quinlan, University of Utah. Salt Lake City, UT

2:45 - 3:10 PM
Germ Cell mutations: A Return to the Roots of the EMGS
Francesco Marchetti, Health Canada

3:10 - 3:30 PM
Nuclear and Mitochondiral Mutagenesis as a Biomarker of Aging and Disease
Jason Bielas, Fred Hutchison Cancer Research Center

Platform


TBA