Environmental Mutagenesis & Genomics Society

50th Annual Meeting, Washington DC

September 19-23, 2019 - Capital Hilton Washington DC

Environmental Mutagenesis and Genomics: The Next Fifty Years

Special Symposium

 Important Dates


3/4/19-Registration is now Open
7/27/19-Early Bird Registration Ends
8/19/19-Advanced Registration Ends


2/22/19-Abstract Submission is now Open
5/15/19-Abstract Submission Deadline
8/29/19-Late Abstracts Deadline

Travel Awards

Travel Award Form Available
5/15/19-Travel Award Deadline

Hotel Information

2/27/19-Reservations Open
8/21/19-Reservation Deadline

Young Scientist Award

EMGS Welcomes You

The EMGS welcomes members and attendees from across the US and around the world. Our diversity is essential to our success, and as your national professional society, we are committed to providing a safe and supportive forum for the communication of world-class science. The EMGS Diversity and Inclusion committee sends a special welcome to members of the LGBT community.  Please reach out to any member of the EMGS Diversity and Inclusion Committee with your comments.

Friday, September 20, 2019

7:00 AM - 8:15 AM

Special Interest Group Meeting

New Technologies
Room: Pan American
Special Interest Group Meeting

Germ Cell and Heritable Effects
Room: Statler
Committee Meeting

Awards/Young Scientist Award
Room: New York

8:30 AM - 12:00 PM

Celebrating 50 Years of EMGS: A Visionary Idea Continues

Co-chairs: David M. DeMarini, US EPA, RTP, NC, Miriam C. Poirier, NCI, Bethesda, MD

Room: Presidential Ballroom

8:30–9:00 AM
Protecting Our Most Vital Assets—Our Genome and Our Environment: The 50-Year Legacy of EMGS
David M. DeMarini, US EPA, RTP, NC

9:00–9:15 AM
The Continuing Evolution of Genetic Toxicity Testing and the EMGS
Errol Zeiger, Errol Zeiger Consulting, Chapel Hill, NC

9:15–9:30 AM
DNA Repair:  From Mechanistic Insights to EMGS Outreach Initiatives
Philip C. Hanawalt, Stanford University, Stanford, CA

9:30–9:45 AM
Stress-Induced Mutagenesis:  From SOS to the DNA Damage Response
Joann B. Sweasy, Yale University School of Medicine, New Haven, CT

9:45–10:00 AM
A Twinkle in Our Founders’ Eyes: The Next Generation of Germ-Cell Mutation Research

Carole L. Yauk, Health Canada, Ottawa, ON, Canada

10:00–10:30 AM
Coffee Break

10:30–10:45 AM
How Much Is Too Much? The Shifting Paradigm for Genetic Toxicity Assessment
Paul White, Health Canada, Ottawa, ON, Canada

10:45–11:00 AM
Epigenetics: Ghosts of Environment Past, Present, and Future
Christopher D. Faulk, University of Minnesota, St. Paul, MN

11:00–11:15 AM
Genotoxicity Biomarkers: The 50-Year Revolution in Molecular Epidemiology

Luoping Zhang, University of California, Berkeley, CA

11:15–11:30 AM
Implementing a Founding Goal of EMGS: Mutagenicity Risk Assessment
Kerry L. Dearfield, USDA/EPA (Retired), Burke, VA

11:30–11:45 AM
EMGS: The Movie!
Hilde van Gijssel, Valley City State University, Valley City, ND

11:45 AM –12:00 PM
The Next 50 Years and Open Discussion
Miriam C. Poirier, National Cancer Institute, Bethesda, MD

12:00 - 1:15 PM

Student/New Investigator Luncheon
Room: Senate

EMGS News Committee Meeting
Room: New York

EMM Board Meeting
Room: Ohio

Endowment Board Meeting
Room: Pan American

1:30 - 3:30 PM

Bridging the Gap Between Science and Policy

Co-chairs: Bret Freudenthal, University of Kansas Medical Center, Kansas City, KS, USA, Stephanie L. Smith-Roe, National Toxicology Program/NIEHS, Research Triangle Park, NC, USA

Room: Presidential Ballroom

1:30-2:00 PM
From Bench to Beltway: Becoming a Science Advocate?
Yvette Seger, Director of Science Policy, Federation of American Societies for Experimental Biology

2:00-2:30 PM
Reaching the Public and Policymakers through Journalism
Meredith Drosback, SciLine, Washington D.C., USA

2:30-3:00 PM
How to Get Washington to Care about Science
Heidi Heitkamp, Past US Senator from North Dakota

3:00-3:30 PM
Science for Policy and Policy for Science, or How to Engage Science in Making Informed Decisions
Kei Koizumi, former advisor in the White House Office of Science and Technology Policy

Understanding the Heritable Effects of Germ-Cell Exposures 50 Years after the Founding of the EMGS

Co-chairs: Carole L. Yauk, Health Canada, Jill Escher, Escher Fund for Autism; Young Investigator Co-Chair: Mathia Colwell, University of Minnesota

Room: South American AB

1:30-2:00 PM
Environmental Determinants of Germ-Cell and Next-Generational Health Epigenomic Mediators of Health
Jacquetta Trasler, McGill University, Montreal, Canada

2:00-2:15 PM
Dissecting the Mechanisms of Epigenetic Transgenerational Inheritance 
Patrick Allard, University of California, Los Angeles, CA, USA

2:15-2:45 PM
Trans- and Intergenerational Epigenetic Inheritance in Allergic Diseases
John Holloway, University of Southampton, United Kingdom

2:45-3:00 PM
DNA Damage in Male Germ Cells and De Novo Germ Line Mutations in Wild Type and OGG1-/- Big Blue® Mice Following Exposure to Benzo(a)pyrene
Ann-Karin Olsen, The Norwegian Institute of Public Health, Dept. of Molecular Biology, Oslo, Norway 

3:00-3:30 PM
Heritable Effects of Agents of General Anesthesia
Anatoly Martynyuk, University of Florida, Gainesville, FL


Platform 1: New Technologies

Co-chairs: Barbara Parsons, US FDA / NCTR; and Kelly Harris, National Center for Toxicological Research

Room: Federal AB

1:30-1:45 PM
The Potential for Fully Automated Scoring of the Cytokinesis Block Micronucleus Cytome Assay Using Imaging Flow Cytometry
Matthew Rodrigues, Luminex Corporation

1:45-2:00 PM
Evidence that Black Cohosh Extracts Destabilize Microtubules, Resulting in Aneugenicity
Stephen Dertinger, Litron Laboratories

2:00-2:15 PM
Repair Assisted Damage Detection (RADD) Harnesses DNA Repair Machinery for in situ DNA Adduct Detection
Natalie Gassman, University of South Alabama College of Medicine

2:15-2:30 PM
Development of a Transcriptomic Biomarker to Detect Histone Deacetylase Inhibition in TK6 Cells
Eunnara Cho, Environmental Health Science and Research Bureau, Health Canada

2:30-2:45 PM
Interlaboratory Validation of the ToxTracker Genotoxicity Assay
Giel Hendricks, Toxys

2:45-3:00 PM
Development of the High-Throughput Genotoxicity Testing Using a Transcriptomic Biomarker
Henghong Li, Georgetown University

3:00-3:15 PM
Assessment of the on- and off-Targets Effects of a CRISPR-Based Cytosine-to-Thymine Base Editor Targeting the LacZ Gene in E. coli
Javier Revollo, Food and Drug Administration

3:15-3:30 PM
Whole Genome Sequencing Analysis of Small and Large Colony Mutants from the Mouse Lymphoma Assay
Xiaoqing Guo, National Center for Toxicological Research, US FDA

3:30 - 4:30 PM

EMGS Award:

The Impact of DNA Damage and Transcription Stress on Aging and the Protection by Nutrition

Jan Hoeijmakers, Erasmus University Medical Center, The Netherlands

Room: Presidential Ballroom

4:30 - 5:00 PM

Flash Talks

Room: Federal AB

Circadian Clock Disruption Impairs the Skin’s DNA Damage Response to Solar UVB and Increases Mutagenicity
Panshak Dakup, Washington State University

Drug-induced Replication Stress Promotes Mutagenic DNA Repair and Genome Instability in Mammalian Genomes
Sheroy Minocherhomji, Amgen

UV-DDB: An Early Responder in the Repair of Oxidative DNA Damage
Namrata Kumar, University of Pittsburgh

Assessing Formaldehyde-induced Hematopoietic Stem Cell Toxicity Derived from BALB/c Mouse Lungs and Nose ex vivo
Laura Magaña, University of California, Berkeley

Microplate Agar (MPA) as a Tool for the Mutagenic Characterization of Dyes Using a more Efficient Strain Battery
Gisela Umbuzeiro, UNICAMP

Machine Learning – Digital Signal Processing and Genomic Signatures to Elucidate the Ancestral Proteobacterial Origin of Mitochondria
Maximillian Soltysiak, University of Western Ontario

Thirdhand Smoke Exposure Impairs DNA Replication and Transcription in Human Lung Cells
Altaf Sarker, Lawrence Berkely National Laboratory

Death by dGTP Starvation
Roel Schaaper, NIEHS

Loss-of-function Mutations in LRRK2 Identify a Subset of Invasive Mammary Carcinomas with Distinct Morphology, Aggressive Behavior and High Mutational Burden
Laurie Sanders, Duke University

Non-Canonical Characteristics of Mutational Signatures Identified by Experimental Modeling
Jiri Zavadil, International Agency for Research on Cancer

Utilization of High Throughput Screening (HTS) Tools to Explain the Mechanism of Misleading in vitro Positive Outcomes: A Case Study
Yax Thakkar, Research Institute for Fragrance Materials Inc.

Environmental Exposures and Omics Research in Pregnant Women and Children: from Metabolomics to DNA Methylation
Gwen Tindula, University of California, Berkeley

5:00 - 7:00 PM

Poster Session 1: Odd numbers

Room: Congressional

7:00 - 9:00 PM

President's Pizza Party

Room: Truman Suite