Environmental Mutagenesis & Genomics Society
Virtual Annual Meeting
September 12-16, 2020
Environmental Genomics:
Mechanisms & Approaches For Genomic Integrity
EMGS 2020 Virtual Meeting
POSTER PRESENTATIONS
Poster Sessions Q&A will be held Saturday, September 12. Presentations are categorized by topic into one of nine 30-minute blocks that will begin at 8:00 a.m. CDT and conclude at 2:30 p.m. CDT. The schedule for the poster presentation blocks is listed below.
BLOCK 1 | 8:00-8:30AM CDT |
BLOCK 6 | 11:00-11:30AM CDT |
BLOCK 2 | 8:30-9:00AM CDT |
BREAK | 11:30AM-1:00PM CDT |
BLOCK 3 | 9:00-9:30AM CDT |
BLOCK 7 | 1:00-1:30PM CDT |
BREAK | 9:30-10:0AM CDT |
BLOCK 8 | 1:30-2:00PM CDT |
BLOCK 4 | 10:00-10:30AM CDT |
BLOCK 9 | 2:00-2:30PM CDT |
BLOCK 5 | 10:30-11:00AM CDT |
|
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 1 | 8:00-8:30AM CDT |
|
|
|
Topic: Applied Genetic Toxicology |
|
|
P1 |
CANCELLED POSTER: Classification of In Vitro Genotoxicants Requiring Metabolic Activation using a Multiplexed Assay (MultiFlowTM) |
Robert Smith |
2190 |
P2 |
A novel genome sequence-based mutagenicity assay using Salmonella typhimurium TA100 model improve mutagenicity and carcinogenicity evaluation of chemicals |
Yuki Otsubo |
2089 |
P3 |
Adopting Duplex Sequencing Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats |
Stephanie L. Smith-Roe, PhD |
2085 |
P4 |
Analysis Of The Cytotoxicity And Genotoxicity of Digested Titanium Dioxide Nanomaterials In Intestinal Cells |
Henriqueta Louro |
2094 |
P5 |
Concentration- and Time-Dependent Metabolic Activation and Genotoxicity of Benzo[a]pyrene in LMH 3D Spheroid |
Tasnia Sharin |
2153 |
P6 |
Detection of DNA damage in sea urchin coelomocytes with fast micromethod |
Fengjia Liu |
2104 |
P7 |
Determining Genotoxic Potential and Mode of Action in a Single Mammalian Cell Assay |
Daniel J Roberts, MS |
2140 |
P8 |
Dihydronicotinamide Riboside Promotes Cell-Specific Cytotoxicity by Tipping the Balance Between Oxidative Stress and Metabolic Regulation |
Manoj Sonavane |
2006 |
P9 |
Dihydroxyacetone Exposure Induces Metabolic Imbalance Induces Mitochondrial Dysfunction |
Raj Mehta |
2010 |
P10 |
Establishing A Hepatic Culture Model To Assess Altered Chemical Susceptibility Due To Pre-existing Liver Steatosis |
Nyssa Tucker |
2054 |
P11 |
Flow Cytometric Evaluation of Genotoxicity Pathways Induced by Non-Covalent DNA-Binders |
Daniel J Roberts, MS |
2178 |
P12 |
Genotoxicity Assessment Using In Vitro Micronucleus Assay and a High-Throughput Transcriptomic Biomarker, TGx-DDI |
Hong Xie |
2249 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 2 | 8:30-9:00AM CDT |
|
|
|
Topic: Applied Genetic Toxicology |
|
|
P13 |
HepaRG™CometChipÒ and HepaRG™ Micronucleus Assay as Non-Animal Alternatives to Follow Up Positive In Vitro Genotoxicity Findings: Case Study with Naphthalene |
Leslie Recio, PhD, DABT |
2192 |
P14 |
HESI Drug Case Study: An Integrated Approach to Pharmaceutical Safety Testing Using High-Throughput CometChip and TGx-DDI Analyses |
Julie Kathleen Buick |
2150 |
P15 |
In vitro mechanism of oxidative stress and DNA damage induction by insulin |
Geema Kodandaraman |
2229 |
P16 |
Particle size and solubility influence the uptake and genotoxicity of nickel compounds in bronchial epithelial BEAS-2B cells – toxic effect of nickel oxide nanoparticles halted by cytochalasin B |
Kirsi Siivola |
2138 |
P17 |
Potency of per- and polyfluoroalkyl substances (PFAS) in exposed human liver cell spheroids using high-throughput transcriptomics |
Anthony John Reardon |
2114 |
P18 |
Quantitative concentration-response analysis using the in vitro micronucleus test to inform genotoxicity evaluation for risk assessment of 292 chemicals |
Byron Kuo |
2143 |
P19 |
S-Allylcysteine Induces Cytotoxicity and Tumoral Growth Reduction in 3D-Multicellular Spheroids Derived from HepG2 cells |
Tainá Keiller Leão |
2176 |
P20 |
Transgenerational effect of N-nitrosodimethylamine in three generations of Drosophila melanogaster |
Rubi Evangelista |
2216 |
|
Topic: DNA Repair & Mutagenic Mechanisms |
|
|
P21 |
Nucleotide Excision Repair Hotspots and Coldspots of UV Damage in Humans |
Wentao Li |
2020 |
P22 |
APE1 Cleavage of Abasic Ribonucleotides Embedded in DNA |
Nicole Hoitsma |
2165 |
P23 |
Autophagy Contributes To Xeroderma Pigmentosum Variant Cell Survival After UVA Light-Induced Oxidative Stress |
Natália Cestari Moreno |
2149 |
P24 |
Carbon Metabolism Impacts the Efficiency of Double-Strand Break Resection in Preparation for Homologous Recombination |
Stephanie Lomonaco |
2126 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 3 | 9:00-9:30AM CDT |
|
|
|
Topic: DNA Repair & Mutagenic Mechanisms |
|
|
P25 |
Characterizing Drosophila mutagen sensitive alleles through a collaborative Course-based Undergraduate Research Experience (CURE) |
Elyse Bolterstein, PhD |
2156 |
P26 |
CometChip Analysis of Human Primary Lymphocytes Enables Quantification of Inter-Individual Differences in the Kinetics of Oxidative Damage Repair |
Simran Kaushal, MIT |
2044 |
P27 |
CRISPR/Cas9 May Cause R-loops |
Madeline Dzikowski |
2148 |
P28 |
DNA Single-strand Break Repair and Signaling by APE1 |
Shan Yan, PhD |
2011 |
P29 |
Droplet Digital PCR-Based Detection Of Mutant mRNAs Conferring Ciprofloxacin Resistance In P. aeruginosa |
Libertad Garcia-Villada |
2077 |
P30 |
Excision of Oxidatively Damaged Bases in G-quadruplexes by the DNA Glycosylases NEIL1 and mNeil3 |
Elizabeth Rose Lotsof |
2023 |
P31 |
Faithful Ligation By DNA Ligase 1 And Its Role In Maintaining Genome Integrity |
Mercedes E. Arana, Ph.D. |
2155 |
P32 |
CANCELLED POSTER: Flap endonuclease 1 cleaves RNAs to resolve R-loops through DNA base excision repair |
Yuan Liu, MD, PhD |
2253 |
P33 |
CANCELLED POSTER: Genoprotective effects of Chaga mushroom (Inonotus obliquus) polysaccharides in UVB-exposed embryonic zebrafish (Danio rerio) through coordinated expression of DNA repair genes |
Jehane Ibrahim, PhD |
2194 |
P34 |
Genotoxicity of Omega-3 fatty acids from the Ames test viewpoint |
Petr Grúz |
2117 |
P35 |
Glycidamide-induced hypermutation in single stranded DNA |
Kathleen Hudson |
2098 |
P36 |
High Resolution in vivo Mapping of Yeast Mitotic DSB Resection Supports a Combined Endo- and Exonucleolytic Mechanism |
Dominic Bazzano |
2136 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 4 | 10:00-10:30AM CDT |
|
|
|
Topic: DNA Repair & Mutagenic Mechanisms |
|
|
P37 |
High-throughput Screening for Resistance to Colon Cancer-associated Carcinogen in Budding Yeast Identifies both DNA Repair and Ribosomal Protein Genes |
Michael T. Fasullo, PhD |
2064 |
P38 |
Impact Of G-quadruplexes On DNA Double-Strand Break Repair By End Joining |
Shruthi Selvaraj |
2154 |
P39 |
Insights from disease and tumor-related mutations in TFIIH and XPG |
Susan Tsutakawa |
2068 |
P40 |
Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs |
Samantha L Sanford |
2185 |
P41 |
Mechanistic Genotoxicity Assessment of Black Cohosh Extract in TK6 cells |
Ji-Eun Seo |
2091 |
P42 |
Metabolic Changes Caused by Endogenous Redox Stress Mirror Alterations Triggered by Exposure to Exogenous Oxidative Agents |
Victoria Placentra |
2101 |
P43 |
Novel roles for the Rad51 paralogs in DNA strand specific damage tolerance |
Kara A. Bernstein, PhD |
2090 |
P44 |
OXIDATIVE DAMAGE ATTENUATES NON-B DNA-INDUCED GENETIC INSTABILITY |
Maha Zewail-Foote |
2038 |
P45 |
Oxidative DNA Damage in Parkinson’s Disease-Associated Genes |
Celeste Marin |
2047 |
P46 |
Probing the Functional Impact of Cancer-Associated Variations within the Interdomain Connector of the Adenine Glycosylase MUTYH |
Cindy Khuu |
2022 |
P47 |
Regulation of budding yeast Hrq1 helicase during DNA crosslink repair |
Thong Luong |
2193 |
P48 |
CANCELLED POSTER: |
Max Fairlamb |
2213 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 5 | 10:30-11:00 AM CDT |
|
|
|
Topic: DNA Repair & Mutagenic Mechanisms |
|
|
P49 |
Structural and Evolutionary Aspects of the Eukaryotic NER Pathway |
Rayana dos Santos Feltrin |
2202 |
P50 |
CANCELLED POSTER: |
Natalie Saini, Postdoc |
2053 |
P51 |
Telomeric 8oxoG Damage Induces Cellular Senescence by Disrupting Telomere Replication |
Ryan Barnes |
2186 |
P52 |
CANCELLED POSTER: Temozolomide attenuates frataxin deficiency through contractions of GAA repeats via base excision repair |
Yanhao Lai |
2048 |
P53 |
The aging immune system drives senescence and dysfunction of peripheral tissues |
Matt Yousefzadeh |
2250 |
P54 |
The BRCA2-interacting protein, PDS5B, and SPIDR are novel Shu complex components |
Sarah R. Hengel |
2093 |
P55 |
The central DNA binding domain of XRCC1 stimulates the repair activity of the DNA glycosylase NTHL1 |
Robyn Maher |
2036 |
P56 |
The effects of metabolic stress on Werner protein-deficient Drosophila |
Elyse Bolterstein, PhD |
2203 |
P57 |
The N-terminus of FBH1 is Critical for Anti-recombinase Activity in Human Cells |
Alexandra Hawks |
2021 |
P58 |
The NEIL1 DNA glycosylase interacts with mitochondrial transcription factor A in presence of DNA via its N-terminal domain |
Nidhi Sharma |
2080 |
P59 |
The Role of Error-Prone polymerases on Tumor Cell Resistance to Temozolomide |
Marcela Teatin Latancia |
2100 |
P60 |
The role of STEAP2 on aggressive prostate cancer traits and androgen responses |
Leia Jones |
2052 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 6 | 11:00-11:30AM CDT |
|
|
|
Topic: DNA Repair & Mutagenic Mechanisms |
|
|
P61 |
TIM-3 polymorphism regulates gene expression and is associated with the susceptibility and clinical prognosis of esophageal squamous cell carcinoma |
Na Wang |
2116 |
P62 |
*Topoisomerase 1 mutants and G-quadruplex-induced genomic instability. (Note: This poster will be presented during Block 9 | 2-2:30PM CDT) |
Alexandra Berroyer* |
2251 |
P63 |
Uncovering how RAD51C mutations contribute to cancer predisposition and sensitize to chemotherapeutics |
Meghan Sullivan |
2120 |
|
Topic: Epigenomics |
|
|
P64 |
A strategy to identify compound-induced DNA methylation changes and potential association to genotoxicity |
Rebekah Beck |
2182 |
P65 |
Development and Validation of a Transcriptomic Biomarker of Chemical-Induced Histone Deacetylase Inhibition in TK6 Cells |
Eunnara Cho |
2170 |
P66 |
Differentially Expressed miRNAs and Functional Pathways Changes in Human Alveolar Epithelial Cells After 1 and 7 Days Exposure to MWCNT-7 or Asbestos |
Célia Ventura |
2163 |
P67 |
Epigenetic Effects of Early Life Aflatoxin Exposure in Rats |
Alisa Dewald |
2246 |
P68 |
miRNAs Associated With DNA Repair Are Upregulated By Environmental Toxicants |
Pawlos Semere Tsegay |
2049 |
P69 |
Neonatal Pb Exposure and DNA Methylation Profiles in Dried Bloodspots |
Luke Benjamin Montrose |
2248 |
P70 |
CANCELLED POSTER: rs2278176 Contributes to the favorable prognosis for metastatic colorectal cancer patients treated with FOLFOX |
You Fu |
2247 |
|
Topic: Gentoxicity Risk Assessment & Public Health |
|
|
P71 |
A Simple Electrophoretic Assay for Quantification of Genomic DNA Damage |
James Eduardo Lago Londero |
2209 |
P72 |
Analytical pipeline for high-throughput gene expression profiling of per-and poly-fluoroalkyl substances (PFAS) in primary human liver cells spheroids to inform read-across |
Andrea Rowan-Carroll |
2103 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 7 | 1:00-1:30PM CDT |
|
|
|
Topic: Gentoxicity Risk Assessment & Public Health |
|
|
P73 |
Antigenotoxic Protective Effect Of Vitamin E And Of 𝞫-Carotene Evaluated By The Comet Assay And The Micronucleus Test In Female Recyclers Exposed To Contaminants Of The Cateura Landfill In Asunción Paraguay |
Deidamia Mercedes Franco de Diana |
2181 |
P74 |
Bisphenol S Induces Changes in C. elegans Maturation, Reproduction, and Genome |
Noelle Jane Chung |
2160 |
P75 |
Determining the association between genomic instability and prevalence of frailty syndrome in Portuguese older adults |
Solange Costa |
2164 |
P76 |
Genotoxicity of Microplastics: Local Aquatic Biomonitoring Suggests Burden of Environmental Plastic Pollution |
Cassandra Haley |
2188 |
P77 |
In Vivo Genotoxicity Assessment Of Multi-Wall Carbon Nanotubes Using Lung Micronucleus Assay |
Katsuyoshi Horibata, PhD |
2042 |
P78 |
Incidence of UVA and UVB Radiation And Its Genotoxic Potential During 2018 In Southern Brazil |
Bruna Cogo Borin |
2208 |
P79 |
Influence of Antioxidant Capacity on Micronucleus Induction by Cigarette Smoke in Various Mammalian Cell Lines |
Tsuneo Hashizume |
2013 |
P80 |
Mode-of-action Analysis of the Induction of Micronuclei by a Flavouring Compound in Vitro. |
Satoru Munakata |
2025 |
P81 |
Mycotoxins and Carcinogenesis: Disentangling Casual Links Through Epidemiological and Mechanistic Investigations |
Liesel Claeys |
2133 |
P82 |
Procarbazine-treated F344 rats have CD48-deficient bone marrow granulocytes with mutations in the Pig-a gene |
Azra Dad |
2180 |
P83 |
The Ames II assay as a component of the GeneTox21 high(er) throughput in vitro genetic toxicity assessment platform |
Nikolai Chepelev, PhD |
2142 |
P84 |
The use of the in vitro micronucleus assay on the genotoxicity assessment of cellulose nanofibrils in mammalian cell lines |
Maria João Silva |
2166 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 8 | 1:30-2:00PM CDT |
|
|
|
Topic: Gentoxicity Risk Assessment & Public Health |
|
|
P85 |
Validation of CACO-2/HT29-MTX Model to Assess the Potential Risk of Ingested Titanium Dioxide Nanoparticles |
Dora Luísa Bispo Rolo |
2084 |
|
Topic: Germ Cell and Heritable Effects |
|
|
P86 |
Effect of repeated exposure to glyphosate on Drosophila melanogaster for fourteen generations |
Hugo Rivas, Biologist |
2207 |
P87 |
Exposure of Drosophila melanogaster females and males to Mitomycin (MMC) produces a different transgenerational effect |
Estefania Arroyo Jilote, student |
2211 |
P88 |
Scrutinizing Variants of Uncertain Significance in the PMS2 gene |
Brandon D'Arcy |
2115 |
P89 |
Smoking and Mutations in Sperm DNA |
Jonatan Axelsson, MD, PhD |
2008 |
|
Topic: In Vivo Mutagenesis |
|
|
P90 |
Duplex Sequencing™ Demonstrates Dose-related Increases in Mutation Frequencies and C>A Transitions in the Bone Marrow of MutaMouse Males Exposed to Benzo(a)pyrene |
Danielle LeBlanc |
2122 |
P91 |
High Precision Risk Assessment System with Large-Scale Control Experiments in the Mouse |
Yoichi Gondo |
2132 |
P92 |
Temporal analysis of mutant frequencies in the bone marrow of MutaMouse males supports the 28+28 design as a single sampling time for in vivo mutagenesis |
Gu Zhou |
2102 |
P93 |
The in vivo Pig-a mutation assay is feasible in primary murine liver cells |
Rebecca Lichtler |
2205 |
P94 |
The rate and spectrum of EMS-induced mutations in the microcrustacean Daphnia: on the prospect of forward genetics |
Marelize Snyman |
2252 |
|
Topic: Other |
|
|
P95 |
Characterization of Rat Testicular Organoids Exposed to Ionizing Radiation |
Dayton Matthew Petibone |
2137 |
P96 |
Dysregulation of NTHL1 and sensitivity to chemotherapeutic agents in human cells |
Anirban Kar |
2050 |
Poster No. |
Session Title |
Author's Name |
Session No. |
|
BLOCK 9 | 2:00-2:30PM CDT |
|
|
|
Topic: Other |
|
|
P97 |
Mechanisms of Activation and Detoxification of Aristolochic Acid and 3-Nitrobenzanthrone |
Viktoriya Sidorenko, PhD |
2152 |
P98 |
Novel LRRK2 transgenic mouse model to understand gene x environment interactions |
Steven D Goodson |
2082 |
P99 |
CANCELLED POSTER: Targeting spike glycoprotein of SARS-corona virus-2 with Chaga mushroom: An in silico study for developing a promising natural therapeutic. |
Jehane Ibrahim, PhD |
2197 |
|
Topic: The Genomics and Data Sciences |
|
|
P100 |
A cross-platform and inter-laboratory evaluation of the TGx-DDI transcriptomic biomarker. |
Andrew Williams |
2141 |
P101 |
A robust analysis pipeline for lineage-based detection of mosaic copy number variants in single cells |
Kai Wang |
2161 |
P102 |
Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance |
Nitika ., Graduate student |
2157 |
P103 |
Investigating Genomic and Mutational Signatures of Organisms Living in Extreme Environments |
Maximillian Soltysiak |
2162 |
P104 |
Optimizing a bacterial laccase for effective oxidation of genotoxic emerging contaminants in wastewater: an in silico approach |
Jia Hao Chen |
2144 |
P105 |
TCDD-inducible poly-ADP-ribose polymerase regulates AHR biology and dioxin toxicity in rat |
Alexandra S. Long, PhD |
2206 |
P106 |
CANCELLED POSTER: Variation in mRNA Expression Patterns Explains Phenotypic Variation in Whole Animal Metabolism, Thermal Tolerance, and Cardiac Metabolic Rate of Fundulus Heteroclitus Populations Experiencing Variable Local Temperatures |
Melissa Drown |
2029 |
|
Late-Breaking Abstract |
|
|
P107 |
Long-term Effects Of Wildfire Exposure During Early Childhood On The Methylome In Rhesus Macaques |
Anthony P. Brown |
2255 |