13th International Conference on Environmental Mutagens

Maintaining Genomic Health in a Changing World

53rd Annual Meeting of the EMGS

August 27 - September 1, 2022 - Ottawa Canada



ICEM 2022 Sponsors

Become a Sponsor  

Diamond Level: 
NIEHS R13 Grant
TwinStrand Biosciences

Platinum Level:
Escher Fund for Autism 

Health and Environmental Sciences Institute
Proctor & Gamble, Co. 
Health Canada 
University of Ottawa 
Carleton University

Gold Level:
Bristol Myers Squibb

Silver Level:
Burroughs Wellcome Fund

United Kingdom Environmental Mutagen Society
Gilead Sciences
National Cancer Institute (NCI)

Bronze Level:
Lhasa Limited

Moltox, Molecular Toxicology, Inc. 
Litron Laboratories


Johnson & Johnson
University of Michigan

European Environmental Mutagenesis and Genomics Society

Japanese Environmental Mutagen and Genome Society
Journal of Biochemistry
Pfizer Inc.
Environmental and Molecular Mutagenesis Journal 
Bill Kaufmann
Genetic Toxicology Association
Society of Toxicology

Satellite Meetings

Samuel H. Wilson Memorial meeting: DNA Damage & Repair

Inspiring basic and applied research on the crucial importance of genome maintenance mechanisms

Date/time: Saturday, August 27, 2022, 8:00am - 3:30pm ET

Chair: Robert Sobol, University of South Alabama, Mobile, Alabama, United States 

Description: This one-day session will highlight cutting edge research from both established leaders and junior trainees on DNA repair mechanisms, with emphasis on their importance for basic and environmental health sciences. The session will exemplify the same dedication to scientific discovery and support for trainees that was a lifelong pursuit of Sam Wilson over his productive and impactful career. You can register for the Samuel H. Wilson Memorial meeting on DNA Damage & Repair on the ICEM 2022 Registration form, whether or not you attend ICEM.

Introduction - Dr. Sam Wilson - Mentor, friend, and leader     
Robert W. Sobol, Mitchell Cancer Institute, University of South Alabama

A Video presentation - In his own words - Sam's career trajectory                   

Mouse DNA polymerase beta - does it work alone?
Robert W. Sobol, Mitchell Cancer Institute, University of South Alabama

Testimonial on Sam Wilson my friend
Susan WallaceUniversity of Vermont, Emeritus

BER processing of oxidative lesions in telomeres
Patty OpreskoUniversity of Pittsburgh & Genome Stability Program, UPMC Hillman Cancer Center

The causes and consequences of making mistakes during DNA synthesis 
Tom Kunkel, National Institute of Environmental Health Sciences, NIH

Polymerases, both big and small, in repair of chromosome breaks     
Dale Ramsden, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill

Aberrant BER and Human Disease
Joann Sweasy, University of Arizona Cancer Center                                      

New Insights into Mitochondrial DNA Replication
Bill Copeland, National Institute of Environmental Health Sciences, NIH

NEIL2: Rule breaker and shape shifter
Sylvie DoubliéUniversity of Vermont

Testimonial on my time working with Sam on the Cutting-edge Perspectives series, and his Editorship of DNA Repair
Phil Hanawalt, Stanford university, Emeritus                 

Mechanisms of PARP activation in the DNA damage response
John Pascal, Université de Montréal

NEIL1 - The tale of a disordered tail
Ash PrakashMitchell Cancer Institute, University of South Alabama

BER, APE1 and nucleases related to BER
John A. Tainer, The University of Texas MD Anderson Cancer Center  

A personal reflection on knowing Sam Wilson
Leona SamsonMassachusetts Institute of Technology, Emeritus

Visualizing Base Excision Repair in Chromatin
Bret FreudenthalUniversity of Kansas Cancer Center

The Role of Nucleotide Excision Repair Proteins in Processing 8-oxoG Base Damage: seeing is believing
Ben Van Houten, University of Pittsburgh & Genome Stability Program, UPMC Hillman Cancer Center

Reflections on Sam's leadership at NIEHS
Rick WoychikDirector, National Institute of Environmental Health Sciences, NIH

9th International Workshops on Genotoxicity Testing (IWGT)

Register for IWGT here!  

Date/time: August 23 - 26, 2022, to be determined

The 8th International Workshops on Genotoxicity Testing (IWGT), a satellite meeting of the ICEM, will be held
August 23 - 26, 2022 at the nearby University of Ottawa. The goal of the IWGT is to gain consensus on current
issues and approaches in genetic toxicology. World-leading experts representing different subject areas are
assembled; recommendations on test systems, strategies and approaches are discussed and debated. The outcome,
with accompanying consensus statements, are published in a peer-reviewed scientific journal. The 8th IWGT will
include Working Groups that collectively address the following topics:

  • Transcriptomic Biomarkers
  • Predictivity of In Vitro Genotoxicity Testing
  • Genotoxicity dose-response Analysis for Potency Comparisons and Risk Assessment
  • In Vivo Genotoxicity Assessment Strategies
  • Statistical Approaches and Data Interpretation

In addition, two plenary sessions will provide state-of-the-art information pertaining to:

  • Epigenotoxicity and Germ Cell Effects
  • Gene Therapy

Guests are welcome to observe and contribute to the discussions. For more information on registration and
participation, please visit https://iwgt.org