Satellite Meetings

Samuel H. Wilson Memorial meeting: DNA Damage & Repair

Inspiring basic and applied research on the crucial importance of genome maintenance mechanisms

Date/time: Saturday, August 27, 2022, 7:00am - 3:40pm ET

Chair: Robert Sobol, University of South Alabama, Mobile, AL, USA

Description: This one-day session will highlight cutting edge research from both established leaders and junior trainees on DNA repair mechanisms, with emphasis on their importance for basic and environmental health sciences. The session will exemplify the same dedication to scientific discovery and support for trainees that was a lifelong pursuit of Sam Wilson over his productive and impactful career. You can register for the Samuel H. Wilson Memorial meeting on DNA Damage & Repair on the ICEM 2022 Registration form, whether or not you attend ICEM.

8:00AM - 8:20AM | Introduction - Dr. Sam Wilson - Mentor, Friend, and Leader     
Robert W. Sobol, Mitchell Cancer Institute, University of South Alabama
     -  A Video presentation - In his own words - Sam's career trajectory                  

8:20AM - 8:45AM | BER Processing of Oxidative Lesions in Telomeres
Patty Opresko, University of Pittsburgh & Genome Stability Program, UPMC Hillman Cancer Center

8:45AM - 9:10AM | Mouse DNA Polymerase Beta - Does it work alone?
Robert W. Sobol, Mitchell Cancer Institute, University of South Alabama

9:10AM - 9:35AM | The Causes and Consequences of Making Mistakes During DNA Synthesis 
Tom Kunkel, National Institute of Environmental Health Sciences, NIH

9:35AM - 10:00AM | Visualizing Base Excision Repair in Chromatin
Bret Freudenthal, University of Kansas Cancer Center

10:00AM - 10:15AM | Coffee Break

10:15AM - 10:25AM | Reflections on Sam's Leadership at NIEHS
Rick Woychik, Director, National Institute of Environmental Health Sciences, NIH

10:25AM - 10:50AM | Mapping the DNA Damage Landscape in Various Species Using Repair Assisted Damage Detection (RADD)
Natalie Gassman, University of Alabama at Birmingham

10:50AM - 11:15AM | The Role of Nucleotide Excision Repair Proteins in Processing 8-oxoG Base Damage: Seeing is believing
Ben Van Houten, University of Pittsburgh & Genome Stability Program, UPMC Hillman Cancer Center

11:15AM - 11:40AM | Aberrant BER and Human Disease
Joann Sweasy, University of Arizona Cancer Center

11:40AM - 12:05PM | Polymerases, both Big and Small, in Repair of Chromosome Breaks     
Dale Ramsden, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill

12:05PM - 12:30PM | Mechanism of Nucleotide Discrimination by the Translesion Synthesis Polymerase Rev1
Tyler Weaver, University of Kansas Medical Center   

12:30PM - 1:00PM | Lunch
(Boxed lunch provided)   

1:00PM - 1:10PM | Testimonial on Sam Wilson my Friend
Susan Wallace, University of Vermont, Emeritus

1:10PM - 1:35PM | NEIL1 - The Tale of a Disordered Tail
Ash Prakash, Mitchell Cancer Institute, University of South Alabama    

1:35PM - 2:00PM | New Insights into Mitochondrial DNA Replication
Bill Copeland, National Institute of Environmental Health Sciences, NIH

2:00PM - 2:25PM | NEIL2: Rule Breaker and Shape Shifter
Sylvie Doublié, University of Vermont

2:25PM - 2:35PM | A Personal Reflection on Knowing Sam Wilson
Leona Samson, Massachusetts Institute of Technology, Emeritus

2:35PM - 3:00PM | Mechanisms of PARP Activation in the DNA Damage Response
John Pascal, Université de Montréal

3:00PM - 3:25PM | BER, APE1 and Nucleases Related to BER
John A. Tainer, The University of Texas MD Anderson Cancer Center  

3:25PM - 3:35PM | Testimonial on my Time Working with Sam on the Cutting-edge Perspectives Series, and his Editorship of DNA Repair
Phil Hanawalt, Stanford University, Emeritus 

3:35PM - 3:40PM | Closing Remarks
Robert Sobol, Mitchell Cancer Institute, University of South Alabama
 

Samuel H. Wilson Memorial Meeting Sponsors

Agilent Technologies c/o Art Guild
Cytoskeleton
Elsevier
Environmental and Molecular Mutagenesis
Gilead
LUMICKS
Moltox
National Institute of Environmental Health Sciences, Office of the Director
New England Bio Labs
Rigaku Americas Corporation
Xpose

9th International Workshops on Genotoxicity Testing (IWGT)

IWGT MOVES TO HYBRID FORMAT

You will be aware that at IWGT our preferred format is on-site attendance in order to maximize interactions with the Working Group members. However, in view of the continued Covid-related travel restrictions, we anticipate many interested scientists may not be allowed to attend IWGT in person. We therefore decided to extend the options to join IWGT remotely, and to move towards a “hybrid” format.

We will therefore now accept registrations from scientists who want to attend IWGT remotely, and to do so scientists should use the below link to register and identify that they will be attending virtually. The registration fee will remain at 250 Euro.

Register for IWGT here!  

Date/time: August 23 - 26, 2022, 8:30AM

The 8th International Workshops on Genotoxicity Testing (IWGT), a satellite meeting of the ICEM, will be held
August 23 - 26, 2022 at the nearby University of Ottawa. The goal of the IWGT is to gain consensus on current
issues and approaches in genetic toxicology. World-leading experts representing different subject areas are
assembled; recommendations on test systems, strategies and approaches are discussed and debated. The outcome,
with accompanying consensus statements, are published in a peer-reviewed scientific journal. The 8th IWGT will
include Working Groups that collectively address the following topics:

• Transcriptomic Biomarkers
• Predictivity of In Vitro Genotoxicity Testing
• Genotoxicity dose-response Analysis for Potency Comparisons and Risk Assessment
• In Vivo Genotoxicity Assessment Strategies
• Statistical Approaches and Data Interpretation

In addition, two plenary sessions will provide state-of-the-art information pertaining to:

• Epigenotoxicity and Germ Cell Effects
• Gene Therapy

Guests are welcome to observe and contribute to the discussions. For more information on registration and
participation, please visit https://iwgt.org

IWGT Flyer